IL-4 and IL-13 Differentially Regulate TLR-Induced Eosinophil-Basophil Differentiation Of Cord Blood CD34+ Progenitor Cells

IL-4RA gene expression in PBMC with regard to place of living and atopy status

“…IL-4 but not IL-13 reduces cord blood progenitor cell Eo/B differentiation in response to LPS and this process is dependent on IL-4R signaling. 27 Simple allergy triggering seems not the only action taken by IL-4. There are studies in cancer in which the expression of IL-4 pathway genes was shown to change depending on disease status.…”