III. Über Lichtwirkung und Leukoderma bei Pityriasis versicolor

Wertheim, Leo

doi:10.1159/000249068

Cited by 1 publication

(7 citation statements)

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“…Independently of each other, Ruete, 20 Kistiakowsky 24 and Wertheim 26 described the complete absence of erythema in depigmented areas during UV irradiation, while the unaffected skin showed marked UV-induced inflammatory reaction. 20,24,26 According to Barney, depigmentation cannot be influenced not even by phototoxic agents. 23 Likewise, therapy studies by El-Gothamy and Abdel-Fattah failed to demonstrate an additional effect of photosensitizing agents in terms of reversibility of depigmentation.…”

Section: Clinic Of Pityriasis Versicolor Albamentioning

confidence: 93%

“…In particular, depigmentation in PVa itself is difficult to treat. It is long‐persisting even under UV irradiation, as shown by Kistiakovskys and Wertheim 24,26 . Jung and Bohnert described repigmentation during UV therapy within 3 weeks after pathogen eradication 25 .…”

Section: Therapymentioning

confidence: 94%

“…In contrast to other depigmentation diseases such as vitiligo, depigmented lesions in PVa are less sensitive to UV light. Independently of each other, Ruete, 20 Kistiakowsky 24 and Wertheim 26 described the complete absence of erythema in depigmented areas during UV irradiation, while the unaffected skin showed marked UV‐induced inflammatory reaction 20,24,26 . According to Barney, depigmentation cannot be influenced not even by phototoxic agents 23 .…”

Section: Clinic Of Pityriasis Versicolor Albamentioning

confidence: 99%

“…In the older literature there are observations reporting high numbers of pathogens (yeast cells and hyphae) in early lesions of PVa, followed by reduction (only demonstration of hyphae) and finally even pathogen‐free depigmented areas 14,24,26 Such a time course could explain the recent controversial findings and shows that depigmentation may outlast the presence of Malassezia yeasts. This would also explain the non‐response of PVa to antimycotics.…”

Section: Clinic Of Pityriasis Versicolor Albamentioning

confidence: 99%

“…So there is marked scaling of early depigmented lesions, followed by complete regression during an intermediate stage in which desquamation is only demonstrable in the marginal region. 7,24,26 Apart from the presence of the pathogen and pityriasiform scaling fluorescence of lesions under UV light is thought to be a third characteristic of the hyperpigmented form of PV. Wood's light examination of the patient (long-wave UV light, approximately 366 nm) allows us to assess the disease extent based on the yellow-greenish fluorescence of affected skin areas.…”

Section: Clinic Of Pityriasis Versicolor Albamentioning

confidence: 99%

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Pityriasis versicolor alba

Thoma¹,

Hj²,

Mayser³

2005

Acad Dermatol Venereol

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Pityriasis versicolor alba is a hypopigmented or depigmented variant of pityriasis versicolor characterized by maculous, partly pityriasiform, scaly depigmented lesions occurring particularly in seborrhoeic areas. Long-persisting hypopigmentation after healing of the pityriasis versicolor was first described by Gudden in 1853. Hypopigmentation and depigmentation were later differentiated as an independent variant of the disease. In 1848, Eichstedt recognized the pathogen-related character of pityriasis versicolor in its hyperpigmented form. Today it is generally accepted that the disease is caused by yeasts of the genus Malassezia, of which nine species are differentiated. It is controversial whether a single species is responsible for the disease. The pathogenesis of depigmentation has not been established. A screening effect by the scale layer as well as toxic effects on pigment synthesis by fungal metabolites have been discussed. With regard to the second mechanism, the newly discovered tryptophan-derived metabolites of M. furfur might be significant. Evidence-based data concerning the therapy of pityriasis versicolor alba do not exist. According to current recommendations, pityriasis versicolor should be rapidly treated with antimycotics, followed by ultraviolet therapy to induce maturation of existent melanosomes and accelerate repigmentation. However, depigmented lesions are difficult to improve by ultraviolet therapy.

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Section: Clinic Of Pityriasis Versicolor Albamentioning

confidence: 93%

Section: Therapymentioning

confidence: 94%