IgG4-related Lung Disease

Raj, Rishi

doi:10.1164/rccm.201306-1121ed

Cited by 30 publications

(25 citation statements)

References 27 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…1,2,3 The information of the incidence rate of IgG4-related lung disease is limited and confined to small case series. 5 In the Italy cohorts, 2.4% (1/41) of the IgG4-RD patients had lung involvement, while it was reported that up to 17.6% (22/125) of the IgG4-RD patients in the United States. 6,7 In the Hong Kong series, 12.7% (7/55) of the patients was found to have this manifestation.…”

Section: Discussionmentioning

confidence: 95%

IgG4-related lung disease on the horizon

Lai

Yim

2018

Hong Kong Bulletin on Rheumatic Diseases

View full text Add to dashboard Cite

Immunoglobulin G4 (IgG4) related lung disease is an emerging entity. We report a case of a 42-year-old man presented with fever and cough with minimal sputum. Chest X-ray revealed diffuse reticulonodular shadows. Extensive investigations were performed, including video-assisted thoracoscopic lung biopsy, which confirmed the diagnosis of IgG4-related disease (IgG4-RD) with lung involvement. This case report aims to illustrate that IgG4-related lung involvement can present as diffuse lung nodules and can affect different pulmonary structures. IgG4-RD should always be considered when a similar scenario is encountered.

show abstract

Section: Discussionmentioning

confidence: 95%

IgG4-related lung disease on the horizon

Lai

Yim

2018

Hong Kong Bulletin on Rheumatic Diseases

View full text Add to dashboard Cite

show abstract

“…IgG4-RLD occurs in 12–50% of patients with IgG4-RD [3], [4], [5]. Mediastinal adenopathy is most common and pulmonary involvement takes the form of pulmonary nodules or masses [3], [6], [7], [8]. As shown in Fig.…”

Section: Discussionmentioning

confidence: 98%

“…IgG4-related lung disease (IgG4-RLD) has been described as interstitial pneumonia and inflammatory pseudo-tumor [2], [3], [4], [5], [6], [7]. Proteinase 3 anti-neutrophil cytoplasmic antibody (PR3-ANCA) is well known as a disease marker in Wegener's granulomatosis [8].…”

Section: Introductionmentioning

confidence: 99%

A case of proteinase 3 anti-neutrophil cytoplasmic antibody (PR3-ANCA) positive/IgG4-related lung disease

Touge

Tomita

Yamasaki

et al. 2017

Respiratory Medicine Case Reports

View full text Add to dashboard Cite

IgG4-related lung disease (IgG4-RLD) is a rare and chronic progressive autoimmune disease. We report a case of IgG4-related inflammatory pseudo-tumor of the lung that was seropositive for proteinase 3 anti-neutrophil cytoplasmic antibody (PR3-ANCA). A 61-year-old male had a mass lesion in the right lower lung field in chest X-ray. Transbronchial lung biopsy resulted in a pathological diagnosis of IgG4-RLD. The condition was improved by hormonal therapy.

show abstract

“…[7,9] Some malignant tumors are identified after IgG4-RD is diagnosed. [10] Therefore, IgG4-RD should be followed up carefully, even after diagnosis is confirmed.…”

Section: Discussionmentioning

confidence: 99%

Immunoglobulin G4-related disease preceded by lung involvement

Abo

Takato²,

Watanabe³

et al. 2017

Medicine

View full text Add to dashboard Cite

Rationale:Immunoglobulin G4-related disease (IgG4-RD) is a systemic condition involving various organs and vessels including the pancreas, bile duct, salivary glands, periorbital tissues, kidneys, lungs, lymph nodes, meninges, and aorta. Recently, some cases of IgG4-RD have been reported, in which only pulmonary lesions were present. It is not known whether IgG4-RD can be diagnosed on the basis of pulmonary lesions only, because increases in serum IgG4 levels and infiltration of IgG4-positive plasma cells into the lung tissue also occur in other inflammatory conditions. A case of IgG-RD that was followed-up for 7 years after onset is described.Patient concerns:Initially, only pulmonary lesions were present; however, other lesions in the submandibular glands, pancreas, periarterial region, and other areas occurred over time, with a gradual increase in serum IgG4 levels.Diagnoses, interventions, and outcomes:Histopathology results from the patient's submandibular gland confirmed the diagnosis of IgG4-RD. Following diagnosis, the patient was treated with corticosteroids immediately, and his symptoms disappeared rapidly.Lessons:Because other diseases, including malignancies, mimic IgG4-RD in clinical and histopathological features, an absolute diagnosis is necessary to avoid missing the presence of underlying diseases. This case more provides insight into the clinical pathology of IgG4-RD.

show abstract

IgG4-related Lung Disease

Cited by 30 publications

References 27 publications

IgG4-related lung disease on the horizon

IgG4-related lung disease on the horizon

A case of proteinase 3 anti-neutrophil cytoplasmic antibody (PR3-ANCA) positive/IgG4-related lung disease

Immunoglobulin G4-related disease preceded by lung involvement

Contact Info

Product

Resources

About