IgE‐mediated allergy to castor bean dust in a landscape gardener

Metz, Gerlinde A. S.; Böcher, D.; Metz, J

doi:10.1034/j.1600-0536.2001.044006366-2.x

Cited by 5 publications

(4 citation statements)

References 3 publications

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“…[80][81][82][83][84][85] Allergy patch testing reveals an IgEmediated inflammatory reaction to ricin although other allergens may be present in the castor bean dust. 83,[86][87][88][89] No cases consistent with direct respiratory tract injury have been reported in the occupational setting, most likely because of the larger particle size of ricin in the castor bean dust or heat inactivation of the plant material.…”

Section: Cleavage Of a And B Chainsmentioning

confidence: 99%

“…An urticarial, IgE-mediated, allergic reaction may occur after handling of the intact castor bean plant or exposure to the castor bean dust or pomace. 83,[86][87][88][89][90] Irritation and the development of pseudomembranous conjunctivitis after ocular exposure to very low ricin concentrations is reported in animals. 3,91 Laboratory Detection Biological Specimens.…”

Section: Cleavage Of a And B Chainsmentioning

confidence: 99%

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Ricin Poisoning

Audi¹,

Belson²,

Patel³

et al. 2005

JAMA

563

292

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ROWING AWARENESS AND concern about ricin, a potent biologic toxin, as a possible terrorist weapon has necessitated a comprehensive review of this poison. 1 The Centers for Disease Control and Prevention (CDC) categorizes ricin as a Category B agent (second-highest priority), as it is moderately easy to disseminate, resulting in low mortality but moderate to high morbidity, and requires specific enhancement of the CDC's diagnostic and disease surveillance capacity. 2 Such agents are not routinely encountered, so heightened awareness in the health care community and a strong public health infrastructure are necessary for detection and response. We therefore have summarized the literature on ricin poisoning and provided recommendations for clinicians and public health professionals dealing with a ricin attack against a civilian population. EVIDENCE ACQUISITION Using PubMed, we searched MEDLINE and OLDMEDLINE databases from January 1950 to August 2005 using the keywords ricin, ricinus communis, ricinine, plant toxins, castor beans, castor dust, and castor oil. Keywords were used alone and with the modifiers toxicity, poisoning, diagnosis, clinical effects, treatment , warfare, chemical terrorism, and weapon. The Chemical and Biological Information Analysis Center (http: //www.cbiac.apgea.army.mil) database was searched for historical and military literature related to ricin tox-CME available online at www.jama.com Context The recent discoveries of ricin, a deadly biologic toxin, at a South Carolina postal facility, a White House mail facility, and a US senator's office has raised concerns among public health officials, physicians, and citizens. Ricin is one of the most potent and lethal substances known, particularly when inhaled. The ease with which the native plant (Ricinus communis) can be obtained and the toxin extracted makes ricin an attractive weapon. Objectives To summarize the literature on ricin poisoning and provide recommendations based on our best professional judgment for clinicians and public health officials that are faced with deliberate release of ricin into the environment. Literature Acquisition Using PubMed, we searched MEDLINE and OLDMEDLINE databases (January 1950-August 2005). The Chemical and Biological Information Analysis Center database was searched for historical and military literature related to ricin toxicity. Book chapters, unpublished reports, monographs, relevant news reports, and Web material were also reviewed to find nonindexed articles. Results Most literature on ricin poisoning involves castor bean ingestion and experimental animal research. Aerosol release of ricin into the environment or adulteration of food and beverages are pathways to exposure likely to be exploited. Symptoms after ingestion (onset within 12 hours) are nonspecific and may include nausea, vomiting, diarrhea, and abdominal pain and may progress to hypotension, liver failure, renal dysfunction, and death due to multiorgan failure or cardiovascular collapse. Inhalation (onset of symptoms is likely within 8 hou...

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Section: Cleavage Of a And B Chainsmentioning

confidence: 99%

Section: Cleavage Of a And B Chainsmentioning

confidence: 99%

Ricin Poisoning

Audi¹,

Belson²,

Patel³

et al. 2005

JAMA

563

292

View full text Add to dashboard Cite

show abstract

“…Type I allergic reactions against different RIPs have already been demonstrated, when people had contact with plants or were treated with medication containing RIPs [18–23]. In a previous study, we could also show that type I allergic reactions against RIPs from elderberry ( Sambucus nigra ) can occur [22].…”

Section: Discussionmentioning

confidence: 76%

Occupational sensitization to ribosome‐inactivating proteins in researchers

Szalai¹,

Schöll²,

Förster-Waldl

et al. 2005

Clin Experimental Allergy

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“…50 The FLN located itself in Cairo and was headed by a nine-member council. The military wing of the FLN, the…”

mentioning

confidence: 99%

Tactical Success is Not Enough: The French in Algeria 1954-1962

Rogers¹

2004

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15.Abstract: This paper focuses on why France, a country with tremendous advantages in resources and military strength was defeated by a group of poorly equipped and largely untrained Algerian insurgents who mainly operated in groups of ten to twenty men and probably never had over fifteen thousand active fighters inside the borders of Algeria.1 The crux of the issue is that France failed to understand the nature of the war and why the Algerians were fighting. This failure led the French to misidentify the Algerian strategic center of gravity and by their actions, to make French centers of gravity, their legitimacy to rule and their will to fight, vulnerable to attack. Demonstrated by analyzing French and Algerian will, intelligence, and civil-military relations.

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IgE‐mediated allergy to castor bean dust in a landscape gardener

Cited by 5 publications

References 3 publications

Ricin Poisoning

Ricin Poisoning

Occupational sensitization to ribosome‐inactivating proteins in researchers

Tactical Success is Not Enough: The French in Algeria 1954-1962

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