Idiopathic ventricular tachycardia in children: curative therapy with radiofrequency ablation

Bakšienė, Dalia; Šileikienė, Rima; Šileikis, Vytautas; Kazakevičius, Tomas; Zabiela, Vytautas; Žėbienė, Migla; Puodžiūkynas, Aras

doi:10.3390/medicina43100103

Cited by 7 publications

(3 citation statements)

References 14 publications

(20 reference statements)

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“…However, ablation should be deferred in young and small children due to the risk of complications and the relatively larger size of the ablation lesion as compared to the child's heart. 596,597 Verapamil is not recommended as the first-line therapy in children ,1 year old because it has been associated with hypotension in some case reports. 542 Of note, all reported patients had either heart failure, overdosing of verapamil, or other concurrent AADs at the time verapamil was given.…”

Section: Smvt In a Patientmentioning

confidence: 99%

2022 ESC Guidelines for the management of patients with ventricular arrhythmias and the prevention of sudden cardiac death

Zeppenfeld¹,

Tfelt-Hansen²,

Riva³

et al. 2022

European Heart Journal

1,151

625

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All experts involved in the development of these guidelines have submitted declarations of interest. These have been compiled in a report and published in a supplementary document simultaneously to the guidelines. The report is also available on the ESC website www.escardio.org/Guidelines See the European Heart Journal online for supplementary data that includes background information and detailed discussion of the data that have provided the basis of the guidelines.Click here to access the corresponding ESC CardioMed chapters.

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Section: Smvt In a Patientmentioning

confidence: 99%

2022 ESC Guidelines for the management of patients with ventricular arrhythmias and the prevention of sudden cardiac death

Zeppenfeld¹,

Tfelt-Hansen²,

Riva³

et al. 2022

European Heart Journal

1,151

625

View full text Add to dashboard Cite

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“…In this study, the ablations in patients with AVNRT were all successful and the success rate was higher than previously reported (95.7–97%) ( 4 ), which may be due to the relatively small sample size of the present study. The ablations in patients with VT were all successful and the success rate was higher than previously reported ( 17 ). Likewise, a possible explanation is the small sample size of our study.…”

Section: Discussionmentioning

confidence: 50%

The efficacy of radiofrequency ablation in the treatment of pediatric arrhythmia and its effects on serum IL-6 and hs-CRP

Jia

Wang

et al. 2017

Experimental and Therapeutic Medicine

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The aim of this study was to investigate the efficacy of radiofrequency ablation in the treatment of pediatric arrhythmia and to assess the changes in serum interleukin-6 (IL-6) and hs-CRP levels after treatment. Hundred and six children with tachyarrhythmia who were admitted to Xuzhou Children's Hospital from November, 2014 to December, 2015 were recruited for study. The efficacies of radiofrequency in the treatment of different types of arrhythmia were analyzed. Successful ablation was found in 104 cases (98.11%) and recurrence was found in 7 cases (6.73%). Among 62 cases of atrioventricular reentrant tachycardia (AVRT), successful ablation was found in 60 cases (96.77%) and recurrence was found in 3 cases (4.84%). Among 33 cases of atrioventricular nodal reentrant tachycardia (AVNRT), successful ablation was found in 33 cases (100%) and recurrence was found in 2 cases (6.06%). Among 5 cases of ventricular tachycardia (VT), successful ablation was found in 5 cases (100%) and no recurrence was found. Among 4 cases of atrial tachycardia (AT), successful ablation was found in 4 cases (100%) and recurrence was found in 1 case (25%). Among 2 cases of atrial flutter (AFL), successful ablation was found in both (100%) and recurrence was found in 1 case (50%). After operation, the levels of IL-6 and hs-CRP were increased and were continually increased within 6 h after operation. The levels of IL-6 and hs-CRP at 24 h after operation were reduced but still higher than preoperative levels. The duration of radiofrequency and ablation energy were positively correlated with the levels of IL-6 and hs-CRP, while the number of discharges was not significantly correlated with either. In conclusion, radiofrequency ablation is a safe and effective treatment for pediatric arrhythmia. Postoperative monitoring of IL-6 and hs-CRP levels is conducive to understanding postoperative myocardial injury and inflammatory response.

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“…Once the mechanism is determined to be a reentrant involving branches of the Purkinje network emanating from the posterior or anterior left fascicles, consideration is needed to search for the appropriate endocardial site of the reentrant circuit guided by specific electrograms of the Purkinje to perform catheter ablation. With improvements in catheter and mapping technology, catheter ablation has become the standard treatment for children and adolescents with idiopathic VT, although reports are primarily of single cases and small series 16,17 . Therefore, experience related to catheter ablation of VT in pediatric patients has been limited.…”

Section: Interventional Treatmentmentioning

confidence: 99%

Idiopathic left fascicular ventricular tachycardia in children and adolescents

Velázquez‐Rodríguez¹,

García-Hernández²,

Silva-Oropeza³

et al. 2022

BMHIM

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Background: Idiopathic ventricular tachycardia (VT) in children with structurally normal hearts is generally unrelated to the risk of sudden arrhythmic death. Still, it may be associated with deterioration in the quality of life. VT involving the fascicular conduction system is the most typical form of idiopathic left VT. In this retrospective study, we describe the experience of the clinical presentation, catheter ablation, and long-term follow-up of left fascicular VT in children. Methods: An electrophysiological study was performed on consecutive children at a single tertiary center. Clinical fascicular left VT was induced by programmed stimulation, and catheter ablation was guided searching for Purkinje potentials. Results: We included 18 patients (0.8 patients/year): 14 (77.8%) males and four females. The mean age of the first VT episode was 8.5 ± 5 years. Intravenous verapamil administration was effective for paroxysmal fascicular VT but not for prevention of recurrences. The mean age at the time of catheter ablation was 11. 1 ± 3.8 years (8 months-16 years). The mean weight was 36.8 ± 16.4 kg (8.7-58 kg). A 100% success rate was observed with catheter ablation after repeated procedures without major complications. Mean follow-up was 2.0 ± 1.2 years (1.0-4.0 years, median 1.5), with permanent success in all patients and no antiarrhythmic drug administration. Conclusions: Fascicular VT has an adverse clinical course in children. In most cases, this condition is drug refractory. Catheter ablation is successful and safe treatment and should represent the first-line approach in symptomatic children.

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Idiopathic ventricular tachycardia in children: curative therapy with radiofrequency ablation

Cited by 7 publications

References 14 publications

2022 ESC Guidelines for the management of patients with ventricular arrhythmias and the prevention of sudden cardiac death

2022 ESC Guidelines for the management of patients with ventricular arrhythmias and the prevention of sudden cardiac death

The efficacy of radiofrequency ablation in the treatment of pediatric arrhythmia and its effects on serum IL-6 and hs-CRP

Idiopathic left fascicular ventricular tachycardia in children and adolescents

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