Idiopathic rhinitis: idiopathic or not?

Carney, A. Simon; Jones, Nick

doi:10.1111/j.1365-2273.1996.tb01724.x

Cited by 23 publications

(29 citation statements)

References 31 publications

(4 reference statements)

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“…[23][24][25][26][27][28] Nasal provocation studies in PNAR have shown that a positive response may exist despite a negative skin test and/or serum specific IgE. [29][30] Additional studies have shown the presence or synthesis of IgE in the nasal mucosa.…”

Section: Discussionmentioning

confidence: 99%

Local IgE production and positive nasal provocation test in patients with persistent nonallergic rhinitis

Rondón¹,

Romero²,

Lopez³

et al. 2007

Journal of Allergy and Clinical Immunology

276

403

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Section: Discussionmentioning

confidence: 99%

Local IgE production and positive nasal provocation test in patients with persistent nonallergic rhinitis

Rondón¹,

Romero²,

Lopez³

et al. 2007

Journal of Allergy and Clinical Immunology

276

403

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“…With ethical committee approval, patients presenting to the Otorhinolaryngology – Head & Neck Surgery Department in Nottingham were screened for possible inclusion in a rhinitis research clinic. The investigative algorithm utilized to establish a diagnosis of isolated idiopathic rhinitis has previously been published in detail 1 . In summary, patients had to fulfil the following criteria:…”

Section: Methodsmentioning

confidence: 99%

mentioning

confidence: 99%

“…Idiopathic rhinitis is now the accepted nomenclature for the condition previously referred to as vasomotor rhinitis, intrinsic rhinitis or non‐allergic perennial rhinitis 1,2 . Knowledge of the pathophysiology of the condition is limited, largely because it is a diagnosis of exclusion and previous studies have had flaws in patient selection 1 . The term vasomotor rhinitis has often been used loosely to describe patients with nasal symptoms who had no evidence of atopy with negative skin tests and normal IgE levels or in whom no evidence of other disease could be found.…”

mentioning

confidence: 99%

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Autoanti-IgE antibodies in patients with allergic and idiopathic rhinitis

Carney¹,

Hooi²,

Powe

et al. 2001

Clin Otolaryngol

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The pathophysiology of idiopathic rhinitis is unknown although evidence is accumulating to suggest that, in a proportion of patients, it may be a more localized form of allergic rhinitis in the absence of other atopic symptoms and markers. Anti-IgE is thought to be a systemic marker of atopy. This study compared serum IgG autoanti-IgE levels in patients with idiopathic rhinitis, perennial allergic rhinitis and normal controls. Serum samples were obtained from 19 patients with idiopathic rhinitis, 17 patients with perennial allergic rhinitis and 10 normal non-rhinitic controls. The presence or absence of IgG1 and IgG4 anti-IgE antibodies was detected using enzyme-linked immunosorbent assays. Eighty-eight percent of the patients with perennial allergic rhinitis had raised levels of autoanti-IgE antibodies in their serum. None of the controls or patients with idiopathic rhinitis showed raised levels (P < 0.001). Although patients with idiopathic rhinitis may exhibit clinical and pathological features of allergy, they do not show raised levels of anti-IgE in their serum.

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“…More than 20% of the population is affected by chronic rhinitis [2][3][4] . Depending on whether an allergic etiology is implicated, non-infectious rhinitis can be subdivided into allergic and non-allergic.…”

Section: Effectiveness Of Endoscopic Posterior Nasal Neurectomy For Tmentioning

confidence: 99%

Original study. Effectiveness of endoscopic posterior nasal neurectomy for the treatment of intractable rhinitis

Arun

Moideen

Mohan

et al. 2017

Romanian Journal of Rhinology

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Effectiveness of endoscopic posterior nasal neurectomy for the treatment of intractable rhinitis INTRODUCTIONRhinitis is an inflammatory condition affecting the lining of the nose, characterized by nasal congestion, rhinorrhea, itching, sneezing and/or post-nasal discharge 1 . More than 20% of the population is affected by chronic rhinitis [2][3][4] . Depending on whether an allergic etiology is implicated, non-infectious rhinitis can be subdivided into allergic and non-allergic. With 600 million of world's population affected, allergic rhinitis is the most prevalent atopic disorder. The incidence of allergic rhinitis is on steady increase 5 . Various etiological factors have been postulated for chronic rhinitis -these include allergy, occupational exposures, hormonal changes, smoking, xylometazoline abuse, etc. The standard treatment strategy is medical (histamine antagonists, leukotriene receptor antagonists, intranasal corticosteroids, etc.) But many times, these therapies show limited effectiveness and cause substantial burden for treatment cost on the long term. In addition, the symptoms of intractable rhinitis can cause social embarrassment with a profound effect on patients' quality of life.Surgical management can be considered in such patients with intractable rhinitis. Various surgical techniques have been documented including Vidian neurectomy 6 , posterior nasal neurectomy, inferior turbinate reduction, with varying success rates [5][6][7][8] . In view of this, we are studying the effectiveness of posterior nasal neurectomy (PNN) in patients who have intractable rhinitis, refractory to maximum medical therapy. The outcome is assessed with patient's level of satisfac-ABSTRACT BACKGROUND. Chronic rhinitis is a clinical condition affecting more than 20% of the world population. The standard treat-

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Idiopathic rhinitis: idiopathic or not?

Cited by 23 publications

References 31 publications

Local IgE production and positive nasal provocation test in patients with persistent nonallergic rhinitis

Local IgE production and positive nasal provocation test in patients with persistent nonallergic rhinitis

Autoanti-IgE antibodies in patients with allergic and idiopathic rhinitis

Original study. Effectiveness of endoscopic posterior nasal neurectomy for the treatment of intractable rhinitis

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