“…The failure of the autonomic nervous system is mainly due to peripheral sympathetic neuron degeneration (Dotson et al, 1990) associated with a decreased catecholamine fluorescence from nerve endings (Kontos et al, 1975;Rubinstein et al, 1978). The postganglionic nature of the disturbance was further supported by the existence of low plasma catecholamine levels (Ziegler et al, 1977;Polinsky et al, 1981;Goldstein et al, 1989) and the failure of tyramine to increase noradrenaline (Nanda et al, 1977;Polinsky et al, 1981).…”