Idiopathic Gingival Fibromatosis: Case Report and Its Management

Jaju, Prashant; Desai, Ankit; Desai, Rajiv S.; Jaju, Sushma

doi:10.1155/2009/153603

Cited by 13 publications

(16 citation statements)

References 12 publications

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“…Autosomal dominant non-syndromic forms have been genetically linked to the chromosome 2p21-p22 and 5q13-q22 8. Recently, a mutation in son of sevenless-1 ( SOS-1 ) gene has been held responsible for this rare hereditary condition 3 7 8 10. When this gene is not mutated, it is involved in the growth of normal healthy gums.…”

Section: Discussionmentioning

confidence: 99%

Non-syndromic hereditary gingival fibromatosis

et al. 2013

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Hereditary gingival fibromatosis is a rare condition characterised by severe gingival hyperplasia that can occur as an isolated disease or as part of a syndrome or chromosomal abnormality. In severe cases, the gingival enlargement may cover the crowns of teeth and cause severe aesthetic, emotional and functional impairment. This case report gives an overview of gingival fibromatosis in a 22-year-old male patient who presented with generalised gingival enlargement.

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Section: Discussionmentioning

confidence: 99%

Non-syndromic hereditary gingival fibromatosis

et al. 2013

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“…There is debate regarding the time of surgery. Eruption of complete set of permanent teeth is the recommended time for surgery [10]. The mother has previously undergone multiple gingivectomies and remained without recurrence.…”

Section: Discussionmentioning

confidence: 99%

Hereditary Nonsyndromic Gingival Fibromatosis: Report of Family Case Series

Peeran

Ramalingam

Peeran

et al. 2013

Case Reports in Dentistry

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Hereditary gingival fibromatosis (HGF) is a rare, benign disorder with slowly progressive enlargement of maxillary and mandibular gingiva. Herewith, we report the first case series of HGF presenting among mother and all of her 3 children. Their complaints included unaesthetic appearance due to gingival growth, malocclusion, and difficulty in mastication. Conventional gingivectomy with oral hygiene measures and regular followup is the treatment of choice for such presentation.

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“…Autosomaldominant forms of gingival fibromatosis, which are usually nonsyndromic, have been genetically linked to the chromosome 2p21-p222 and 5q13-q22 (23). Recently, a mutation in the son of sevenless-1 (SOS-1) gene has been suggested as a possible cause of isolated (nonsyndromic) gingival fibromatosis, but no definite linkage has been established (24). Although over the past few years increasing efforts have been made to understand the genetic, molecular and cellular basis of gingival enlargement of IGF patients, it has been impaired by the intense clinical, genetic and biologic heterogeneity of the disease.…”

Section: Etiologymentioning

confidence: 99%