Idiopathic Dilated Cardiomyopathy: Clinical Profile of 100 Patients

Banerjee, Sajal K; Rahman, Fazlur; Salman, Mohammad; Siddique, Abu; Zaman, SM Mustafa; Anam, Khairul; Rahman, Mukhlesur; Ahmed, Khurshed; Rasheed, Michael A.; Akhter, Nargis; Faruque, M; Jamiluddin, Mir; Haque, Kmhs Sirajul; Hoque, Harisul

doi:10.3329/uhj.v6i1.7182

Cited by 3 publications

(5 citation statements)

References 12 publications

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“…The mean LVIDd and LVIDs were found 6.5 ±0.5 and 5.2±0.5 respectively which were similar to previous study 29 .On echo-color Doppler study 59% patients had mitral regurgitation (MR) grade-l, 20% MR grade-ll, 14% MR grade-lll and 7% had no MR. Previous study 29,32 related to ischemic cardiomyopathy and dilated cardiomyopathy also showed similar pictures. We, the physicians have to take challenge to manage these patients daily.…”

Section: Discussionsupporting

confidence: 69%

Clinical, Electrocardiographic and Echocardiographic Profile of Ischemic Cardiomyopathy: An analysis of 100 cases.

et al. 2021

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Background: Ischemic heart disease (IHD) is one of the leading cause of morbidity and mortality worldwide. Ischemic cardiomyopathy (ICM) is a delayed complication of IHD that arises as dilated cardiomyopathy with depressed ventricular function, which cannot be attributed entirely to coronary artery obstruction or ischemic injury. Objectives: To evaluate the clinical, electrocardiographic and echocardiographic profile of patients presenting with ischemic cardiomyopathy. Methods: In this cross sectional observational study 100 patients of ischemic cardiomyopathy admitted in hospital or visited OPD in NICVD, Dhaka from March’15 to Sept’15 were studied. Enrollment of the patients were done after fulfilling the inclusion and exclusion criteria. Clinical, electrocardiographic and echocardiographic data were collected then data analysis was done. Results: Data analysis of 100 patients was showed age range was 40-80 years and mean age was 61.4±7.9 years. 79% subjects were male. Most common symptoms were dyspnea (93%), chest pain(73%), palpitation (39%) and edema (23%). Most patients were in NYHA functional class lV (43%). 64% cases had history of anterior myocardial infarction (MI), 22% had inferior MI, 25% had H/O PTCA and 7% had CABG. 71% subjects had tachycardia, 65% had lungs basal rales, 56% had systolic blood pressure below 100 mmhg and 25% had edema. ECG findings was as follows sinus rhythm (85%), Sinus tachycardia 71%, AF 15%, LBBB 34%, RBBB 12%, pathological Q in anterior surface 65% and inferior surface 21%, non specific ST-T changes 41% and PVCs was found in 17%.On echocardiography ,anterior wall hypokinesia was seen in 52% and global hypokinesia in 43%. Mean left ventricular ejection fraction (LVEF) was 31±5.9% and mean left ventricular internal diastolic diameter (LVIDd) was 6.5±0.4 cm. (59%) subjects had mitral regurgitation (MR) grade-l and 20% had MR grade-ll. Conclusion: The clinical presentation of ischemic cardiomyopathy varies from patient to patient. Severity of symptoms correlates with severity of left ventricular systolic dysfunction, left ventricular diameter and mitral regurgitation grade . Anterior Myocardial infarction has more chance to develop ischemic cardiomyopathy. Bangladesh Heart Journal 2020; 35(2) : 121-127

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Section: Discussionsupporting

confidence: 69%

Clinical, Electrocardiographic and Echocardiographic Profile of Ischemic Cardiomyopathy: An analysis of 100 cases.

et al. 2021

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“…Sonowal et al 11 in their study on idiopathic DCM showed that most of the patients presented with dyspnea (70.97%) followed by palpitation (64.52%) and Fowler et al 12 found that dyspnea (89%), dependent edema (89%) were the most common presenting symptom, which are similar to our study. Banerjee et al 10 in their study observed that most common symptoms were dyspnea (86%) and cough (75%) though we got cough as presenting symptom in only 20% cases. These clinical findings e.g.…”

Section: Discussionmentioning

confidence: 52%

“…Sonowal et al 11 in their study found that 61.29% were male and 38.71% were female showing male female ratio to be 1.6:1. However, male-female ratio was reported to be higher (4:1) by Kuhn et al 13 and 2.33:1by Banerjee et al 10 In this study 45(90.0%) patients had dyspnea, 43(86.0%) fatigability, 39(78.0%) swelling of legs, 35(70.0%) PND, 34(68%) orthopnoea, 30(60%) palpitation, 24(48.0%) angina, 18(36.0%) abdominal pain, 10(20.0%) cough, and 4(8%) was found asymptomatic. Sonowal et al 11 in their study on idiopathic DCM showed that most of the patients presented with dyspnea (70.97%) followed by palpitation (64.52%) and Fowler et al 12 found that dyspnea (89%), dependent edema (89%) were the most common presenting symptom, which are similar to our study.…”

Section: Discussionmentioning

confidence: 90%

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Clinical profile of patients with Idiopathic Dilated Cardiomyopathy in a Tertiary Care Hospital of Bangladesh

Hoque¹,

Rahman²,

Alam³

et al. 2019

Bangladesh Crit Care J

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Background: High prevalence of Chronic heart failure due to Idiopathic Dilated Cardiomyopathy (DCM) is animportant cause of heart failure in Bangladesh. This study was carried out to find the clinical characteristics of thepatients with Idiopathic DCM, so that the data can be used to treat symptoms and improve survival and treatment. Methodology: This prospective observational study was carried out in the Department of Cardiology, BIRDEMGeneral Hospital, Dhaka, Bangladesh from January 2012 to December 2018. Total 50 consecutive admittedpatients fulfilling the criteria of Idiopathic DCM were studied. Clinical information, findings fromEchocardiography and other relevant investigations were collected for analysis. Results: Among total 50 patients, 30(60.0%) were male and 20(40.0%) were female. Majority 20(40.0%) patientsbelonged to age 51-60 years and their mean age was found 55.34±13.24 years. Using NYHA (New York HeartAssociation) functional status classification of the patients, 18(36.0%) patients were found in NYHA class I,15(30.0%) in class II, 12(24.0%) in class III and 5(10.0%)in class IV. Almost all patients presented with three basicsymptoms i.e. exertional dyspnea, easy fatigability and pedal edema. Orthopnea, Paroxosmal Nocturnal Dyspnoea(PND), palpitation & chest pain wewe also reported in almost half of the patients. Mean pulse was found88.78±15.75 beat/min, respiratory rate 20.79±6.48 breath/min, BMI 23.12±3.29 kg/m2, systolic BP 119.03±22.22mmHg and diastolic BP 75.00±12.54 mmHg. Bilateral basal crepitation 45(90.0%), Pedal edema 43(86.0%),Raised JVP 39(78.0%), Hepatomegaly 35(70.0%) were also found. Third heart sound in 34(68.0%), Pan systolicmurmur of Mitral regurgitation 40(80.0%), Pansystolic murmur of Tricuspid regurgitation was present in42(84.0%) among study patients. Mean left ventricular ejection fraction was found 30.44 ±4.91%, LVIDs 5.24±0.51cm and LVIDd 6.18 ±0.52 cm. Conclusion: Majority of the Idiopathic DCM patients belonged to age 51-60 year age group with malepredominance and clinical presentation was variable. Bangladesh Crit Care J September 2019; 7(2): 86-89

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“…CM, in advanced countries contributes up to 40% of the proportion of total patients with HF (4). Banerjee et al reports HF in 75% patients and death during hospital stay in 8% patient with CM (5). HF causes decline in quality of life (6) with an observed 5-year survival of 26-52% (7) and thus it is labeled as more malignant that cancer (8).…”

Section: Introductionmentioning

confidence: 99%

Survival Outcome in Patients with Cardiomyopathy Detected by Gated SPECT Myocardial Perfusion Imaging

Sarker¹,

Nasreen

Nisa

et al. 2019

Bangladesh J. Nuclear Med.

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Objective: Quantitative assessment of LV dysfunction and viability through gated SPECT myocardial perfusion imaging (GSMPI) in addition to being diagnostic surrogate of cardiomyopathy (CM), are being increasingly reported as a predictor of adverse outcome in CM. This study was conducted to investigate the survival outcome in patients diagnosed with CM by GSMPI at National Institute of Nuclear Medicine & Allied Sciences (NINMAS). Patients and methods: Patients who underwent Tc-99m Sestamibi GSMPI at NINMAS from January 2007 to December 2009 and were diagnosed with CM were retrospectively included in the study. The GSMPI parameters of diagnosis of CM were a left ventricular ejection fraction (EF) at rest of less than 40% with a corresponding end diastolic left ventricular volume (EDV) of more than 130 ml. Telephonic interviews of those patients were conducted in the year 2015 to obtain their clinical follow up data. Results: Fifty two patients (M/F=50/2) were diagnosed to have CM over a period of three years. Follow up data of 19 (M/F=18/1) patients with mean age 52.9±7.4 (38-65), EF 29.1±6.6 (18-39), EDV 211±45.4 (135-320) were available. Nine (47.4%) patients were alive at the time of follow up and 10 (52.6%) patients were found to be deceased. Thus, in this patient group one and five year survival was estimated to be 68 and 47%. Comparison of means of pretest probability score, GSMPI parameters of LV function and viability revealed no difference (p > 0.05) between survivors and non-survivors. Test of equality of survival distributions for management strategies revealed no difference either (Log Rank significance, p > 0.05). Conclusions: Five year survival in this study group diagnosed with CM by GSMPI was 47% where pretest probability score, GSMPI parameters and management strategies were not associated with difference of survival. Bangladesh J. Nuclear Med. 21(2): 81-86, July 2018

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Idiopathic Dilated Cardiomyopathy: Clinical Profile of 100 Patients

Cited by 3 publications

References 12 publications

Clinical, Electrocardiographic and Echocardiographic Profile of Ischemic Cardiomyopathy: An analysis of 100 cases.

Clinical, Electrocardiographic and Echocardiographic Profile of Ischemic Cardiomyopathy: An analysis of 100 cases.

Clinical profile of patients with Idiopathic Dilated Cardiomyopathy in a Tertiary Care Hospital of Bangladesh

Survival Outcome in Patients with Cardiomyopathy Detected by Gated SPECT Myocardial Perfusion Imaging

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