“…In parallel with these diverse definitions, a wide-ranging aetiology has been described. Preiser’s disease has been used synonymously for idiopathic avascular necrosis, meaning avascular necrosis without clear aetiology (Allen et al, 1983; Alnot et al, 1990; Dossing et al, 1994; Ekerot et al, 1981; Ferlic et al, 1989; Gupta et al,1992; Herbert et al, 1994; Jensen et al, 1995; Lauder et al, 2006; Martini et al, 1995; Parkinson et al, 1991; Zadeh et al, 1996; Zeng et al, 2001). Several nontraumatic causes have been described including steroid use (Chang et al, 1993; Kawai et al, 1983; Virik et al, 2001), systemic disease (Aptekar et al, 1974; Tate et al, 2000), chemotherapy (Chang et al, 1993; Harper et al, 1984), and smoking (Chang et al, 1993).…”