Idiopathic Aquagenic Wrinkling of the Palms in Korean Patients

Palmar wrinkling after water exposure in a child

“…Numerous treatment options have been reported, such as topical 20 % aluminum chloride solution, acetic acid, iontophoresis, botulinum toxin injection as well as topical preparations with corticosteroids, urea and salicylic acid, as well as 12 % ammonium lactate [4,8,12]. Based on our experience as well as the published report by Itin et al, antihistamine therapy is promising and has few side effects [1].…”

“…Aquagenic wrinkling of the palms is more common in women than in men and appears predominantly during puberty or post-puberty [4]. Aquagenic wrinkling of the palms (also known as transient aquagenic hyperwrinkling and aquagenic syringeal acrokeratoderma) is characterized by excessive wrinkling of the palms with whitish papules and possible desquamation following exposure to water [5].…”

Two Cases of Aquagenic Wrinkling of the Palms in Korean Healthy Women: Easily Overlooked Disease

“…AWP mainly occurs in Caucasian adolescent women. The occurrence of AWP in Asian is very rare and up to date all five Asian AWP cases occurred only in young men and screening for CFTR mutations were not evaluated 4 . In these cases, CFTR mutations test was evaluated and all patients were young healthy women.…”

Schwellung und Faltenbildung der Hände nach Wasserkontakt bei einem Kind

“…Frauen sind insgesamt häufiger betroffen und erkranken meist während oder nach der Pubertät [4]. Das AA (auch bekannt als aquagenes Pseudoakrokeratoderm und aquagenes syringeales Akrokeratoderm) ist charakterisiert durch eine übermäßige palmare Faltenbildung mit weißlichen Papeln und möglicher Desquamation nach Wasserkontakt [5].…”