IDF Diabetes Atlas: Global estimates of the prevalence of diabetes for 2011 and 2030

Abstract

This paper builds on previous IDF estimates and shows that the global diabetes epidemic continues to grow. Recent studies show that previous estimates have been very conservative. The new IDF estimates use a simple and transparent approach and are consistent with recent estimates from the Global Burden of Disease study. IDF estimates will be updated annually.

Diabetes Confers Little to No Increased Risk of Postoperative Complications After Hip Fracture Surgery in Geriatric Patients

“…Diabetes mellitus is a common chronic disease that has been identified as a risk factor for sustaining a hip fracture in elderly patients [4,13,23,27]. However, to our knowledge, no previous studies have stratified patients with diabetes to evaluate the association of noninsulindependent and insulin-dependent diabetes on rates of postoperative complications, lengths of stay, or readmissions after surgical stabilization of elderly patients with hip fractures.…”

“…Diabetes mellitus is a widespread, chronic disease that is estimated to affect greater than 300 million people worldwide, including between 5% to 13% of the US population [4,6,24,27]. The global disease burden of diabetes is expected to surpass 550 million people by 2030 [27].…”

Serum miRNA Signatures Are Indicative of Skeletal Fractures in Postmenopausal Women With and Without Type 2 Diabetes and Influence Osteogenic and Adipogenic Differentiation of Adipose Tissue–Derived Mesenchymal Stem Cells In Vitro

“…(2) Numbers are projected to at least double, or in case of T2D with the obesity epidemic almost triple, by 2030. (3) Both diseases are detrimental to the bone resulting in an increased risk for fragility fractures (4) : the lifetime risk to sustain an osteoporotic fracture ranges between 40% to 50% in women (5) and in T2D, the risk of having a fragility fracture lies even higher and varies dependent on the skeletal site between 20% and 160% in elderly women. (6) Given the substantial morbidity, mortality, and costs that emanate from osteoporotic (7) or T2D-related fractures, (8,9) proper recognition of populations at increased fracture risk is indispensable.…”

Anti-diabetic activity of stigmasterol from soybean oil by targeting the GLUT4 glucose transporter

“…It occurs either when the pancreas does not produce enough insulin or when the body cannot effectively utilize the insulin that is produced [1]. Excessive blood glucose, which is often seen as the main characteristic of DM, is sometimes accompanied by lipids and protein metabolism disorder [2].…”