Identifying the predictors of needling after XEN gel implant

Midha, Neha; Rao, Harsha L.; Mermoud, André; Mansouri, Kaweh

doi:10.1038/s41433-018-0206-0

Cited by 38 publications

(31 citation statements)

References 14 publications

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“…The need for both postoperative needling and 5-FU injections following XEN Gel Stent insertion is fairly well documented [ 15 ]. Specifically, in several prospective studies of XEN insertion with subconjunctival mitomycin-C needling rates have ranged from 30.7–43.2%, although it has been reported as low as 2.4% [ 16 , 17 , 18 , 19 , 20 , 21 ].…”

Section: Discussionmentioning

confidence: 99%

Bilateral XEN Gel Stent Implantation in Juvenile-Onset Open-Angle Glaucoma

Klug

Valle

2020

Case Rep Ophthalmol

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The purpose of the current case is to report the successful management of juvenile-onset open-angle glaucoma with bilateral XEN Gel Stent (Allegran Inc., Irvine, CA) implantation in a patient first diagnosed during pregnancy with co-existing dysautonomia. Treatment with the XEN Gel Stent provided dramatic reductions in intraocular pressure (IOP), and glaucoma medications sustained up to 23 months postoperatively. The success of this case may suggest that this minimally invasive procedure could be an effective treatment option for younger patients who require substantial reductions in IOP and glaucoma medication burden.

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Section: Discussionmentioning

confidence: 99%

Bilateral XEN Gel Stent Implantation in Juvenile-Onset Open-Angle Glaucoma

Klug

Valle

2020

Case Rep Ophthalmol

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“…[23] In a study to assess the predictors of needling post-XEN gel stent implantation, Midha et al reported that eyes with lower IOP on day 1 were less likely to require a needling procedure and that a significant association was seen between lower day 1 IOP and lesser number of post-operative needling procedures. [29] The probability of needling was up to 80% in patients having a postoperative day 1 IOP >20 mm Hg while this number decreased to 35% if the day 1 IOP was <10 mm Hg. However, no significant association was observed between day 1 IOP and needling interventions in phaco-XEN eyes.…”

Section: Bleb Revision/needlingmentioning

confidence: 97%

XEN Gel stent: A Review

Dangda¹,

Castanos²,

Do³

et al. 2019

cleverjournal

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Over the last decade, several new surgical devices and treatment options have been developed for the management of glaucoma. Together, known as micro-invasive glaucoma surgery, they aim to provide a safer approach to glaucoma surgery. Although the early devices were used to either stent or ablate a segment of the trabecular meshwork, newer devices such as the XEN gel stent (Allergan Inc., Dublin, Ireland), offer the possibility of creating a safer, more predictable filtering bleb. Since its FDA approval in 2016, several retrospective case series and prospective studies have highlighted the efficacy of the XEN gel stent with regards IOP lowering and reduction in the need for glaucoma medications. The XEN gel stent has also been shown to have a favorable safety profile in terms of intraoperative and post-operative complications. The major concern is the need for bleb intervention in the form of needling and injection of anti-fibrotic agents. This review focuses to summarize the current knowledge on the XEN gel stent for treatment of various subtypes of glaucoma.

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“…spowodowanego spadkiem lub z brakiem filtracji [13]. Zwraca bowiem uwagę fakt, że wbrew oczekiwaniom u znaczącego odsetka chorych leczonych tą metodą (32-47%) występuje konieczność wykonania needlingu lub chirurgicznej rewizji miejsca filtracji [11,15,21,23,24]. Ze względu na stosunkowo mniejszy i mniej burzliwy wypływ cieczy wodnistej pod spojówkę niż po zabiegach trabekulektomii, częściej dochodzi do obklejenia spojówką ostium zewnętrznego ujścia implantu.…”

Section: Rycinaunclassified

“…chirurgii minimalnie inwazyjnej (MIGS, minimally invasive glaucoma surgery) [5,[7][8][9]. MIGS została zdefiniowana przez Amerykańskie Towarzystwo Jaskrowe i FDA w 2014 r. jako: "procedury zwiększające odpływ cieczy wodnistej z oka, z zastosowaniem implantów lub bez, z dostępu z zewnątrz lub wewnątrz, wykonywane bez lub z minimalnym nacięciem twardówki" [10,11]. Zabiegi te mają może mniejszą skuteczność niż złoty standard chirurgii jaskry, ale za to większy profil bezpieczeństwa [5].…”

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