Identification of two intestinal vitamin D-dependent calcium-binding proteins in the X-linked hypophosphataemic mouse

Baker, L. R. I.; Clark, Michael; Fairclough, P. D.; Goble, Hilary

doi:10.1016/0006-291x(84)90851-9

“…The aim of this work was to investigate whether calbindin-D2s K was present in the rat intestinal nervous system and endocrine-like cell population. Indeed, the presence of small amounts of this protein in rat and mouse duodenum has been reported [6,25,39]. Results were compared with those we and others obtained using antibodies raised against some of the most widely distributed gut neuropeptides, i.e.…”

Section: Introductionmentioning

confidence: 94%

Calbindin-D28K and the peptidergic neuroendocrine system in rat gut: an immunohistochemical study

Resibois¹

1988

Biology of the Cell

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Calbindin-D28K was immunohistochemically localized in myenteric and submucosal plexuses throughout the rat intestine. Calbindin-D28K immunoreactivity was found in about half of myenteric neurons and in more than 90% of submucosal neurons. Calbindin-D28K was also observed in nerve processes running inside ganglia, muscle layers and lamina propria. No correlation could be established between the presence of calbindin-D28K and the distribution of neuropeptides localized in this study (VIP, enkephalin, somatostatin and substance P). In addition, some endocrine-like cells of the ileum were calbindin-D28K-positive. Half of these endocrine cells also contained neurotensin but none of the other neuropeptides investigated.

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“…Indeed, the presence of small amounts of this protein in rat and mouse duodenum has been reported [6,25,39]. Indeed, the presence of small amounts of this protein in rat and mouse duodenum has been reported [6,25,39].…”

Section: Introductionmentioning

confidence: 98%

Calbindin‐D_28K and the peptidergic neuroendocrine system in rat gut: an immunohistochemical study

Résibois

¹

,

Vienne

²

,

Pochet

³

1988

Biology of the Cell

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Calbindin-D28K was immunohistochemically localized in myenteric and submucosal plexuses throughout the rat intestine. Calbindin-D28K immunoreactivity was found in about half of myenteric neurons and in more than 90% of submucosal neurons. Calbindin-D28K was also observed in nerve processes running inside ganglia, muscle layers and lamina propria. No correlation could be established between the presence of calbindin-D28K and the distribution of neuropeptides localized in this study (VIP, enkephalin, somatostatin and substance P). In addition, some endocrine-like cells of the ileum were calbindin-D28K-positive. Half of these endocrine cells also contained neurotensin but none of the other neuropeptides investigated.

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Low levels of intestinal calbindm-D28k in X-linked hypophosphatemic mice

Tohmon

¹

,

Fukase

²

,

Fujita

³

1989

Bone and Mineral

0

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Identification of two intestinal vitamin D-dependent calcium-binding proteins in the X-linked hypophosphataemic mouse

Cited by 5 publications

References 4 publications

Calbindin-D28K and the peptidergic neuroendocrine system in rat gut: an immunohistochemical study

Calbindin-D28K and the peptidergic neuroendocrine system in rat gut: an immunohistochemical study

Calbindin‐D_28K and the peptidergic neuroendocrine system in rat gut: an immunohistochemical study

Low levels of intestinal calbindm-D28k in X-linked hypophosphatemic mice

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Identification of two intestinal vitamin D-dependent calcium-binding proteins in the X-linked hypophosphataemic mouse

Cited by 5 publications

References 4 publications

Calbindin-D28K and the peptidergic neuroendocrine system in rat gut: an immunohistochemical study

Calbindin-D28K and the peptidergic neuroendocrine system in rat gut: an immunohistochemical study

Calbindin‐D28K and the peptidergic neuroendocrine system in rat gut: an immunohistochemical study

Low levels of intestinal calbindm-D28k in X-linked hypophosphatemic mice

Contact Info

Product

Resources

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Calbindin‐D_28K and the peptidergic neuroendocrine system in rat gut: an immunohistochemical study