Identification of the rare yeast <i>Cutaneotrichosporon (Trichosporon) debeurmannianum</i> from diabetic foot infection

Yoo, In Young; Heo, Woong; Kwon, Joo An; Lee, Mi Ran; Park, Yeon‐Joon

doi:10.1002/jcla.24785

Cited by 3 publications

(2 citation statements)

References 20 publications

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“…However, the unexpected discovery of C. debeurmannianum as a core member of lichen communities in this study is noteworthy. This fungus, which has previously been isolated as a rare basidiomycete yeast, has been found in clinical samples, including cases of diabetic foot infections 18,19 . Previously, Spribille's research garnered attention by molecularly demonstrating the presence of basidiomycete yeasts in various lichens 20 .…”

Section: Discussionmentioning

confidence: 99%

Cross-border comparison of mycobiomes in Parmelia and Peltigera lichens from Turkey and South Korea

Yang,

Woo,

Sesal

et al. 2023

Preprint

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Lichens, traditionally considered as a simple partnership primarily between fungi and photobiont, are, in reality, complex ecosystems comprised of a multitude of microorganisms. Endolichenic fungi represent fungi residing within lichen thalli without causing any disease symptoms. Various factors, including the host lichen species and environmental conditions, can influence the structure of the lichen mycobiome. To investigate which factor, host genus or location, has a greater impact on the lichen mycobiome, we conducted a comparative analysis of mycobiomes within Parmelia and Peltigera collected from both Turkey and South Korea, using high-throughput sequencing. In terms of taxonomic diversity, the lichen mycobiome does not show significant differentiation based on host phylogeny or geographical distance, suggesting similar characteristics. Location differences exert a stronger influence on the lichen mycobiome than the host genus. We have identified the core mycobiomes of Parmelia and Peltigera, and these two core mycobiomes share common fungal strains including basidiomycete yeast. Our study enhances our understanding of lichen mycobiomes, shedding light on their taxonomic diversity, the factors influencing their composition, and the core members and specialists within these intricate ecosystems.

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Section: Discussionmentioning

confidence: 99%

Cross-border comparison of mycobiomes in Parmelia and Peltigera lichens from Turkey and South Korea

Yang,

Woo,

Sesal

et al. 2023

Preprint

View full text Add to dashboard Cite

show abstract

“…However, the unexpected discovery of C. debeurmannianum as a core member of lichen communities in this study is noteworthy. This fungus, which has previously been isolated as a rare basidiomycete yeast, has been found in clinical samples, including cases of diabetic foot infections [ 48 , 49 ]. Previously, Spribille’s research garnered attention by molecularly demonstrating the presence of basidiomycete yeasts in various lichens [ 50 ].…”

Section: Discussionmentioning

confidence: 99%

Continental scale comparison of mycobiomes in Parmelia and Peltigera lichens from Turkey and South Korea

Yang,

Woo,

Sesal

et al. 2024

BMC Microbiol

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Background Lichens, traditionally considered as a simple partnership primarily between mycobiont and photobiont, are, in reality, complex holobionts comprised of a multitude of microorganisms. Lichen mycobiome represents fungal community residing within lichen thalli. While it is acknowledged that factors like the host lichen species and environmental conditions influence the structure of the lichen mycobiome, the existing research remains insufficient. To investigate which factor, host genus or location, has a greater impact on the lichen mycobiome, we conducted a comparative analysis of mycobiomes within Parmelia and Peltigera collected from both Turkey and South Korea, using high-throughput sequencing based on internal transcribed spacer region amplification. Results Overall, the lichen mycobiome was dominated by Capnodiales (Dothideomycetes), regardless of host or location. At the order level, the taxonomic composition was not significantly different according to lichen genus host or geographical distance. Hierarchical clustering of the top 100 abundant ASVs did not clearly indicate whether the lichen mycobiome was more influenced by host genus or location. Analyses of community similarity and partitioning variables revealed that the structure of the lichen mycobiome is more significantly influenced by location than by host genus. When analyzing the core mycobiome by host genus, the Peltigera mycobiome contained more ASV members than the Parmelia mycobiome. These two core mycobiomes also share common fungal strains, including basidiomycete yeast. Additionally, we used chi-squared tests to identify host genus-specialists and location-specialists. Conclusions By comparing lichen mycobiomes of the same genera across different countries, our study advances our comprehension of these microbial communities. Our study elucidates that, although host species play a contributory role, geographic distance exerts a more pronounced impact on the structure of lichen mycobiome. We have made foundational contributions to understanding the lichen mycobiome occupying ecologically crucial niches. We anticipate that broader global-scale investigations into the fungal community structures will provide more detailed insights into fungal residents within lichens.

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Identification of the rare yeast Cutaneotrichosporon (Trichosporon) debeurmannianum from diabetic foot infection

Yoo

Heo

Kwon

et al. 2022

Clinical Laboratory Analysis

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Background Diabetic foot infection is the most common complications of diabetes mellitus. Although most of the diabetic foot infections has been known to be caused by aerobic and anaerobic bacteria, mycotic diabetic foot infection caused by Candida species has also been reported recently. Here, we present the first case of diabetic foot infection caused by Cutaneotrichosporon debeurmannianum (previously known as Trichosporon debeurmannianum). Methods A 68‐year‐old diabetic male patient was admitted for management of the necrosis of the big toe. Wound swab culture was performed three times, and each time after 5 days of incubation, beige‐colored, wrinkled, and rough colonies were observed on chocolate agar plate. Results The isolate was identified as C. debeurmannianum with the matrix‐assisted laser desorption ionization‐time of flight mass spectrometry system (MicroIDSys, ASTA corp.). For confirmation, the sequencing for ITS1/ITS2 and D1/D2 ribosomal DNA was also performed, and the isolate was confirmed as C. debeurmannianum with 100% identity. The isolate exhibited low minimum inhibitory concentrations (MICs) for azoles and high MICs for all echinocandins. Conclusion Considering that usual incubation time for bacterial culture of open wound specimens is only 48 h, it is important to include the request for fungus culture to detect pathogen in diabetic foot lesion.

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Identification of the rare yeast Cutaneotrichosporon (Trichosporon) debeurmannianum from diabetic foot infection

Cited by 3 publications

References 20 publications

Cross-border comparison of mycobiomes in Parmelia and Peltigera lichens from Turkey and South Korea

Cross-border comparison of mycobiomes in Parmelia and Peltigera lichens from Turkey and South Korea

Continental scale comparison of mycobiomes in Parmelia and Peltigera lichens from Turkey and South Korea

Identification of the rare yeast Cutaneotrichosporon (Trichosporon) debeurmannianum from diabetic foot infection

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