To analyze the impact of volcanic rocks in the Offshore Indus Basin on hydrocarbon reservoir formation, seismic data interpretation, seismic data inversion, and sea–land correlation analysis were carried out. The results show that, longitudinally, volcanic rocks are mainly distributed at the top of the Cretaceous system or at the bottom of the Paleocene, and carbonate rock platforms or reefs of the Paleocene–Eocene are usually developed on them. On the plane, volcanic rocks are mainly distributed on the Saurashtra High in the southeastern part of the basin. In terms of thickness, the volcanic rocks revealed by drilling in Karachi nearshore are about 70 m thick. We conducted sparse spike inversion for acoustic impedance in the volcanic rock area. The results show that the thickness of the Deccan volcanic rocks in the study area is between 250 and 750 m which is thinning from southeast to northwest. Based on sea–land comparison and comprehensive research, the distribution of volcanic rocks in the Indian Fan Offshore Basin played a constructive role in the Mesozoic oil and gas accumulation in the Indus offshore. Therefore, in the Indian Fan Offshore Basin, attention should be paid to finding Mesozoic self-generated and self-stored hydrocarbon reservoirs and Cenozoic lower-generated and upper-stored hydrocarbon reservoirs.