Identification of raloxifene as a novel α-glucosidase inhibitor using a systematic drug repurposing approach in combination with cross molecular docking-based virtual screening and experimental verification

Curcumin nanoparticles: physicochemical fabrication, characterization, antioxidant, enzyme inhibition, molecular docking and simulation studies

“…For this purpose, inhibition of glucose hydrolyzing enzymes like amylase and glucosidase is necessary. [21][22][23] The alpha-amylase (-1,4-glucan-4-glucanohydrolases) is the most prominent enzyme as secretory product of salivary gland and that of pancreas. It is responsible for the conversion of mixture of complex carbohydrates to oligosaccharides and disaccharides by hydrolysis.…”