Identification of QTLs associated with p-coumaric acid and ferulic acid in barley

Zhao, Han; Gao, Huaizhou; Ye, Lingzheng; Adil, Muhammad Faheem; Ahsan, Muhammad; Zhang, Guoping

doi:10.1007/s10681-019-2526-y

Cited by 2 publications

(2 citation statements)

References 33 publications

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“…Fifteen genotypes of O. aristatus were assessed for the quality of phytochemicals and pharmacological activities in all records of this discussion. Phenolic is a group metabolite associated with several pharmacological activities; therefore, the content of phenolics (TPC) in the plant needs to be determined 29,30 . TPC ranged 1.48 mg GAE/g DW (A6) to 36.08 (A15) mg GAE/g DW (Table 1).…”

Section: Discussionmentioning

confidence: 99%

Genotype selection for phytochemical content and pharmacological activities in ethanol extracts of fifteen types of Orthosiphon aristatus (Blume) Miq. leaves using chemometric analysis

Batubara

Komariah

Sandrawati

et al. 2020

Sci Rep

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Orthosiphon aristatus (Blume) Miq. of the Lamiaceae family, called as kumis kucing in Indonesia, is a valuable medicinal plant for their pharmacological properties. The present study comprised of fifteen genotypes of O. aristatus was undertaken to evaluate the genotypes based on phytochemical content and pharmacological activities of leaves ethanol extract. Chemometric analysis (correlation and principal component analysis) was also used to investigate the genetic variability based on phytochemical content and pharmacological activities of O. aristatus genotypes. Results of phytochemical characterization showed that total phenolic ranged from 1.48 to 36.08 (maximum in A15) mg GAE/g DW, total flavonoid ranged from 0.10 to 3.07 (maximum in A15) mg QE/g DW, sinensetin ranged from 0.36 to 4.02 (maximum in A11) mg/g DW, and rosmarinic acid ranged 0.06 to 7.25 (maximum in A7) mg/g DW. Antioxidant activity was tested using DPPH and FRAP assay. Antioxidant results showed that DPPH ranged from 1.68 to 15.55 (maximum in A15) μmol TE/g DW and FRAP ranged from 0.07 to 1.60 (maximum in A1 and A7) μmol TE/g DW. The genotype A8 showed the highest cytotoxic activities against HeLa (66.25%) and MCF-7 (61.79%) cell lines. Maximum α-glucosidase inhibitory activity was recorded in genotype A2 with the value of 62.84%. The genotypes A1, A2, A7, A11, and A15 were identified as superior based on their phytochemicals content and pharmacological activities coupled with chemometric analysis. This finding is important for breeding studies and also the pharmaceutical perspective of O. aristatus.

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Section: Discussionmentioning

confidence: 99%

Genotype selection for phytochemical content and pharmacological activities in ethanol extracts of fifteen types of Orthosiphon aristatus (Blume) Miq. leaves using chemometric analysis

Batubara

Komariah

Sandrawati

et al. 2020

Sci Rep

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“…Phenolic compounds, known to possess antioxidant properties, are a group of metabolites that need to be quantified in plants (Nurcholis et al 2018;Han et al 2019). The Total Phenolic Compound contents (TPC) in all the extracts are presented in Table 1, with the highest level found in A10 (13.80 mg GAE/g DW).…”

Section: Discussionmentioning

confidence: 99%

Phytochemical content and antioxidant capacity of ethyl acetate extracts from fifteen Orthosiphon aristatus leaves genotypes

BOVANI,

LIWANDA,

BATUBARA

et al. 2024

Biodiversitas

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Abstract. Bovani RP, Liwanda N, Batubara I, Ambarsari L, Nurcholis W. 2024. Phytochemical content and antioxidant capacity of ethyl acetate extracts from fifteen Orthosiphon aristatus leaves genotypes. Biodiversitas 25: 763-769. Orthosiphon aristatus (Blume) Miq., also known as kumis kucing in Indonesia, is a medicinal plant belonging to the Lamiaceae family that contains various phytochemical compounds with antioxidant properties. This study investigated the phenolic content, flavonoid, rosmarinic acid, sinensetin, and antioxidant capacity of 15 genotypes of O. aristatus ethyl acetate extracts. Therefore, 15 genotypes were analyzed using quercetin as the standard for Total Phenolic Content (TPC) using a colorimetric method with gallic acid and Total Flavonoid Content (TFC). Sinensentin and rosmarinic acid were measured by High-Performance Liquid Chromatography (HPLC). Antioxidant capacity was determined using Trolox as a standard antioxidant by 2-Diphenyl Picrylhydrazyl (DPPH) and Ferric Reducing Antioxidant Power (FRAP) assays. The results revealed a diverse range of phytochemical compounds, with total phenolic content ranging from 3.39 to 13.80 mg GAE/g DW, total flavonoid content from 0.20 to 1.43 mg QE/g DW, rosmarinic acid from 0.02 to 0.19 mg/g DW, and sinensetin from 1.61 to 21.67 mg/g DW. Furthermore, the antioxidant assays demonstrated varying degrees of efficacy, with DPPH ranging from 2.09 to 13.98 ?mol TE/g DW and FRAP from 0.07 to 2.96 ?mol TE/g DW. Genotypes A10, A11, and A12 exhibited superior phytochemical contents and antioxidant capacities, highlighting their potential as valuable sources of medicinal compounds.

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Identification of QTLs associated with p-coumaric acid and ferulic acid in barley

Cited by 2 publications

References 33 publications

Genotype selection for phytochemical content and pharmacological activities in ethanol extracts of fifteen types of Orthosiphon aristatus (Blume) Miq. leaves using chemometric analysis

Genotype selection for phytochemical content and pharmacological activities in ethanol extracts of fifteen types of Orthosiphon aristatus (Blume) Miq. leaves using chemometric analysis

Phytochemical content and antioxidant capacity of ethyl acetate extracts from fifteen Orthosiphon aristatus leaves genotypes

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