Identification of hibernating myocardium with myocardial contrast echocardiography

Toušek, Petr; Pěnička, Martin; Tintěra, Jaroslav; Línková, Hana; Gregor, P

doi:10.1016/j.ijcard.2007.05.113

Cited by 11 publications

(6 citation statements)

References 16 publications

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“…Specificity of contrast echocardiography was higher than for magnetic resonance imaging (72% and 52%, respectively; P < 0.01). 23 Our results are similar to studies that used RTMCE for detecting myocardial viability. RTMCE techniques (qualitative and quantitative analysis) had good sensitivity but low specificity for predicting resting functional recovery.…”

Section: Detection Of Myocardial Viability By Contrast Echocardiographysupporting

confidence: 87%

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Qualitative and Quantitative Real Time Myocardial Contrast Echocardiography for Detecting Hibernating Myocardium

et al. 2011

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Section: Detection Of Myocardial Viability By Contrast Echocardiographysupporting

confidence: 87%

“…The sensitivity of preserved myocardial perfusion during contrast echocardiography for segmental function recovery of akinetic segments was 78% and was similar to magnetic resonance imaging (87%; P = NS). Specificity of contrast echocardiography was higher than for magnetic resonance imaging (72% and 52%, respectively; P < 0.01) 23 …”

Section: Discussionmentioning

confidence: 84%

Qualitative and Quantitative Real Time Myocardial Contrast Echocardiography for Detecting Hibernating Myocardium

et al. 2011

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“…Tousek et al [65] reported that MCE had similar sensitivity but higher specificity to delayed-enhanced MRI.…”

Section: Recent Trends In Viability Assessmentmentioning

confidence: 99%

Myocardial Viability: What We Knew and What Is New

Shabana

El‐Menyar

2012

Cardiology Research and Practice

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Some patients with chronic ischemic left ventricular dysfunction have shown significant improvements of contractility with favorable long-term prognosis after revascularization. Several imaging techniques are available for the assessment of viable myocardium, based on the detection of preserved perfusion, preserved glucose metabolism, intact cell membrane and mitochondria, and presence of contractile reserve. Nuclear cardiology techniques, dobutamine echocardiography and positron emission tomography are used to assess myocardial viability. In recent years, new advances have improved methods of detecting myocardial viability. This paper summarizes the pathophysiology, methods, and impact of detection of myocardial viability, concentrating on recent advances in such methods. We reviewed the literature using search engines MIDLINE, SCOUPS, and EMBASE from 1988 to February 2012. We used key words: myocardial viability, hibernation, stunning, and ischemic cardiomyopathy. Recent studies showed that the presence of viable myocardium was associated with a greater likelihood of survival in patients with coronary artery disease and LV dysfunction, but the assessment of myocardial viability did not identify patients with survival benefit from revascularization, as compared with medical therapy alone. This topic is still debatable and needs more evidence.

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“…8) are those that become evident during physical or pharmacological stress and disappear during resting [61,62]. The same technique may be applied in the detection of damaged but viable myocardium ("hibernating myocardium") [63,64] as dysfunctional segments demonstrating contrast enhancement have better recovery of wall motion than segments with no reflow. Myocardial contrast echocardiography offers real-time frame rates and the direct correlation between flow and wall motion.…”

Section: Clinical Applications Of Organ Perfusionmentioning

confidence: 99%