Identification of FecXG and FecB Mutations and its Association with Litter Size in Kacang and Boerka Goat

Abstract

The Kacang goat is one of Indonesia's prolific native goat breeds, while the Boerka goat is a crossbreed between Kacang and Boer goats. It is widely known that the ovulation rate and litter size in sheep breeds are significantly impacted by the BMP15 (FecX G ) and BMPR-1B (FecB) gene alterations. Based on this knowledge, the study's objective was to determine the presence of BMP15 and BMPR-1B gene polymorphisms and how they affected the prolific traits of Kacang and Boerka goats. This study indicates that the FecX G and FecB mutations were associated with litter size in Kacang and Boerka goat breeds. The FecX G has two genotypes in both Kacang and Boerka goats, namely homozygote wild type ++ and heterozygote mutant carrier G+ with a litter size of 1.

Genetic Screening of FecXG Polymorphism in Saanen Goat (Capra hircus) Breed in Türkiye

“…Nevertheless, more research is need that reveals the genetic structures of goats in terms of fertility genes. Maskur et al (2023) reported that the mutations of FecX G (c.718C>T) and FecB (c.746A>G) were in Indonesian Kacang and Boerka goats. Another study examining the S32G mutation in the BMP15 gene in 18 breeds of goats, reported a monomorphic structure in Saanen goats (Feng et al, 2014).…”