Identification of cytochrome P450 1B-like sequences in two teleost fish species (scup, Stenotomus chrysops and plaice, Pleuronectes platessa) and in a cetacean (striped dolphin, Stenella coeruleoalba)

Godard, Céline A. J.; Leaver, Michael J.; Said, Maya R.; Dickerson, R.; George, Stephen; Stegeman, John J.

doi:10.1016/s0141-1136(00)00052-0

Cited by 30 publications

(14 citation statements)

References 6 publications

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“…The cytochrome P450 constitute a multigene family of enzymes involved in the oxidation of many endogenous and xenobiotics substrates (Godard et al 2000). CYP450, identified in most vertebrates, is widely used as biomarker when assessing exposure to contaminants in environmental system (Williams et al 2000;Mc Clain et al 2003).…”

Section: Discussionmentioning

confidence: 99%

Evaluation of the gene expression changes in Nile tilapia (Oreochromis niloticus) as affected by the bio-removal of toxic textile dyes from aqueous solution in small-scale bioreactor

2010

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A laboratory-scale bioremediation unit was designed, built and tested for the bio-removal of several Direct textile dyes. Four experiments were carried out to assess the efficiency of the bioremediation unit using Aspergillus niger fungal strain. Three commonly used Direct dyes and textile dyes mixture (simulated effluent: Direct brown, Direct violet, Direct green) were tested in this study. The strain of A. niger was efficient in the removal of the three Direct dyes. The decolorization percentages of the dyes after 24 h of incubation were 56.2, 51.7, and 95.4% for Direct brown, Direct green, Direct violet dyes, respectively. The percentages increased up to 79.4, 86.4, and 96.7% after 72 h of incubation for the same dyes, respectively. The results also showed that the fungal strain reduced the chemical oxygen demand values of simulated dye effluents from 165 to 564 mg/l with most of the dyes. The assessment of bioremediation products on biomodel was conducted using a fresh water fish. The liver and brain of Nile tilapia were tested to evaluate the expression of genes coding for several proteins related to stress such as metallothioneins (MTs), cytochrome P450 (CYP450), and heat shock proteins (HSPs). To assess the alterations in the gene expression, ten animals from each group were killed after 4 weeks of treatment. The results revealed significant increases in the brain and hepatic mRNA levels of all stress protein genes MT, CYP450, Hsp70a, b, and Hsp47 in the fish groups treated with industrial Direct violet, green, and brown dye water. Exposure of tilapia to bioremediation products after treatment with A. niger fungi reduced the over-expression of the stress protein genes in the brain and liver tissues.

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Section: Discussionmentioning

confidence: 99%

Evaluation of the gene expression changes in Nile tilapia (Oreochromis niloticus) as affected by the bio-removal of toxic textile dyes from aqueous solution in small-scale bioreactor

2010

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“…The cytochromes P450 constitute a multigene family of enzymes involved in the oxidation of many endogenous and xenobiotics substrates (Godard et al, 2000). CYP1A, identified in most vertebrates, is widely used as biomarker when assessing exposure to contaminants in environmental system (Williams et al, 2000;Mc Clain et al, 2003).…”

Section: Discussionmentioning

confidence: 99%

Rearing density influences the expression of stress-related genes in sea bass (Dicentrarchus labrax, L.)

Gornati

Papis

Rimoldi

et al. 2004

Gene

158

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“…Although the ability to metabolise PCBs was previously thought to be less well developed in cetaceans than in pinnipeds (Boon et al, 1997), implying that cetaceans may be more sensitive to effects of exposure to POPs, more recent evidence (reviewed by Hall et al, 2006) suggests that this may not be the case. Immunoreactive proteins recognised by heterologous CYP2B antibodies are present in several cetaceans including harbour porpoises (White et al, 1994;Goksøyr, 1995;Hummert et al, 1995) and CYP1B-like amino acid sequences are present in striped dolphin cDNA (Godard et al 2000).…”

Section: Introductionmentioning

confidence: 99%

Bioaccumulation of persistent organic pollutants in female common dolphins (Delphinus delphis) and harbour porpoises (Phocoena phocoena) from western European seas: Geographical trends, causal factors and effects on reproduction and mortality

Pierce

Santos

Murphy

et al. 2008

Environmental Pollution

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High PCB levels were recorded in porpoises and common dolphins from European coasts. AbstractConcentrations of polychlorinated biphenyls (PCBs) in blubber of female common dolphins and harbour porpoises from the Atlantic coast of Europe were frequently above the threshold at which effects on reproduction could be expected, in 40% and 47% of cases respectively. This rose to 74% for porpoises from the southern North Sea. PCB concentrations were also high in southern North Sea fish. The average pregnancy rate recorded in porpoises (42%) in the study area was lower than in the western Atlantic but that in common dolphins (25%) was similar to that of the western Atlantic population. Porpoises that died from disease or parasitic infection had higher concentrations of persistent organic pollutants (POPs) than animals dying from other causes. Few of the common dolphins sampled had died from disease or parasitic infection. POP profiles in common dolphin blubber were related to individual feeding history while those in porpoises were more strongly related to condition.

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Identification of cytochrome P450 1B-like sequences in two teleost fish species (scup, Stenotomus chrysops and plaice, Pleuronectes platessa) and in a cetacean (striped dolphin, Stenella coeruleoalba)

Cited by 30 publications

References 6 publications

Evaluation of the gene expression changes in Nile tilapia (Oreochromis niloticus) as affected by the bio-removal of toxic textile dyes from aqueous solution in small-scale bioreactor

Evaluation of the gene expression changes in Nile tilapia (Oreochromis niloticus) as affected by the bio-removal of toxic textile dyes from aqueous solution in small-scale bioreactor

Rearing density influences the expression of stress-related genes in sea bass (Dicentrarchus labrax, L.)

Bioaccumulation of persistent organic pollutants in female common dolphins (Delphinus delphis) and harbour porpoises (Phocoena phocoena) from western European seas: Geographical trends, causal factors and effects on reproduction and mortality

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