Identification of Critical Biological Parameters Affecting Gastrointestinal Absorption

DeSesso, John M.; Mavis, Richard D.

doi:10.21236/ada236507

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Bioavailability Of Lead In Various Media1

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Cited by 3 publications

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References 35 publications

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“…Lead uptake occurs in certain segments of the small intestine (12). The relative efficiency of the gut in various animal species to absorb lead, compared to a measure of potential lead intake rate such as body surface area, would be a useful predictor for enteric lead uptake rates (61,89). Weis and LaVelle (62) showed a much greater ratio of gut absorptive surface to body surface area for the human than for the rat.…”

Section: Bioavailability Of Lead In Various Mediamentioning

confidence: 99%

Uses and limits of empirical data in measuring and modeling human lead exposure.

Mushak¹

1998

Environ Health Perspect

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Section: Bioavailability Of Lead In Various Mediamentioning

confidence: 99%

Uses and limits of empirical data in measuring and modeling human lead exposure.

Mushak¹

1998

Environ Health Perspect

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Anatomical and Physiological Parameters that Influence Gastrointestinal Absorption

DeSesso

Jacobson

Williams

2012

Encyclopedia of Drug Metabolism and Interactions

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The rate at which ingested compounds are absorbed into the bloodstream from the gastrointestinal (GI) tract and extent to which they are absorbed are governed by the physical‐chemical properties of the ingested compounds, the presence and identity of other substances in the GI tract, and the anatomical and physiological characteristics of the GI tract. This chapter describes the anatomical and physiological similarities and differences between humans and some common laboratory animals, with an emphasis on the absorptive surface area of the GI tract, the time it takes for materials to move through the GI tract, and the nature of the GI contents.

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Response to the Commentary of Wu et al.

DeSesso

Jacobson

2002

Food and Chemical Toxicology

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Identification of Critical Biological Parameters Affecting Gastrointestinal Absorption

Cited by 3 publications

References 35 publications

Uses and limits of empirical data in measuring and modeling human lead exposure.

Uses and limits of empirical data in measuring and modeling human lead exposure.

Anatomical and Physiological Parameters that Influence Gastrointestinal Absorption

Response to the Commentary of Wu et al.

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