Identification of Adverse Drug Reactions in Geriatric Inpatients Using a Computerised Drug Database

Egger, Tobias; Dormann, Harald; Ahne, Gabi; Runge, Ulrich; Neubert, Antje; Criegee-Rieck, Manfred; Gaßmann, K-G; Brune, Kay

doi:10.2165/00002512-200320100-00005

Cited by 64 publications

(55 citation statements)

References 26 publications

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“…As one would expect, the number of drugs on admission was associated with the number of diagnoses and age. Thus, elderly patients with several concurrent diseases treated with a range of drugs had the highest [3,7,[25][26][27][28][29]. Interestingly, patients with kidney failure on admission also had more pDDIs, which is probably related to the drug class taken by these patients.…”

Section: Discussionmentioning

confidence: 99%

Potential drug-drug interactions and admissions due to drug-drug interactions in patients treated in medical departments

Fokter

Možina

Brvar

2010

Wien Klin Wochenschr

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Section: Discussionmentioning

confidence: 99%

Potential drug-drug interactions and admissions due to drug-drug interactions in patients treated in medical departments

Fokter

Možina

Brvar

2010

Wien Klin Wochenschr

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“…4 With an aging population, the number of patients on multiple medications will increase and the likelihood of clinically significant DDIs will escalate. 6,20 The need for more specific DDI screening tools increases as the number of prescriptions being filled rises.…”

Section: ■■ Discussionmentioning

confidence: 99%

Evaluation of the Performance of Drug-Drug Interaction Screening Software in Community and Hospital Pharmacies

Abarca

Colón

Wang³

et al. 2006

JMCP

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harmacists play an important role in protecting the public from the dangers posed by potential drug-drug interactions (DDIs), which have been identified as an important subset of medication errors.1 They are uniquely trained to recognize medication-related problems and have the opportunity to review the medication profiles of patients in the inpatient and outpatient setting before dispensing occurs.One of the tools that pharmacists rely on to review medication profiles for DDIs is computerized screening for DDIs. Computerized screening for DDIs and other potential drug-related problems is embedded within most pharmacy computer systems that are used in community and hospital pharmacies and also is included in the prospective, online drug utilization review provided by pharmacy benefit managers. While manual review of medication regimens can be performed by pharmacists, recognition of DDIs without the use of an aid (e.g., drug interaction reference, computer program) only identifies approximately 70% of DDIs in a 2-drug regimen and the proportion decreases substantially as the number of medications increases.2 Thus, computerized DDI screening has the potential to significantly improve the recognition of potentially harmful DDIs beyond what can be achieved with manual review alone. 3Research on the performance of computerized DDI screening software and the references they are based on have found problems in the ability to provide consistent information and screen for clinically significant DDIs. [4][5][6][7][8] For example, in 2001, Hazlet et al. ABSTRACTBACKGROUND: Computerized drug-drug interaction (DDI) screening is widely used to identify potentially harmful drug combinations in the inpatient and outpatient setting.OBJECTIVE: To evaluate the performance of drug-drug interaction (DDI) screening software in identifying select clinically significant DDIs in pharmacy computer systems in community and hospital pharmacies.

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“…This Þ nding differed from reports of other studies. [8,9] Women have been reported to be at greater risk for ADRs. [10] However, in this study a male preponderance was noticed.…”

Section: Discussionmentioning

confidence: 99%

Adverse drug reactions in nephrology ward inpatients of a tertiary care hospital

Joshua¹,

Devi²,

Guido³

2007

Indian J Med Sci

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Identification of Adverse Drug Reactions in Geriatric Inpatients Using a Computerised Drug Database

Cited by 64 publications

References 26 publications

Potential drug-drug interactions and admissions due to drug-drug interactions in patients treated in medical departments

Potential drug-drug interactions and admissions due to drug-drug interactions in patients treated in medical departments

Evaluation of the Performance of Drug-Drug Interaction Screening Software in Community and Hospital Pharmacies

Adverse drug reactions in nephrology ward inpatients of a tertiary care hospital

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