Identification of a human group C rotavirus in Malaysia

Rasool, Nassar B. G.; Hamzah, Mustafar Kamal; Jegathesan, M; Wong, Yick Hei; Qian, Yuan; Green, Kim Y.

doi:10.1002/jmv.1890430302

Cited by 17 publications

(16 citation statements)

References 27 publications

(14 reference statements)

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“…In the current study, it is interesting that the virus was detected in the stools from a 1-yearold male and a 3-year-old female, as against most group C human rotaviruses being detected in children aged b 3 years and in adults. This ®nding is similar to the identi®cation of group A human rotaviruses mainly in infants and young children aged`2 years [Rodger et al, 1982;Dimitrov et al, 1983;Nicolas et al, 1983;Espejo et al, 1984;Rasool et al, 1994;Jiang et al, 1995] with severe diarrhoea. It con®rms further the results of other studies [Penaranda et al, 1989;Caul et al, 1990;Oishi et al, 1993;Jiang et al, 1995;Kuzuya et al, 1998;Steele and James, 1999;Sebata and Steele, 1999] indicating that human group C rotaviruses are more common than anticipated previously.…”

Section: Discussionmentioning

confidence: 51%

Detection of human group C rotaviruses in Nigeria and sequence analysis of their genes encoding VP4, VP6, and VP7 proteins

Adah

Wade

Oseto³

et al. 2001

Journal of Medical Virology

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In a survey on the etiology of acute gastroenteritis in infants and young children in Nigeria, group C human rotaviruses were detected in two of 112 rotavirus positive stool specimens collected between 1999 and 2000. The VP7, VP6, and VP4 genes of the two Nigerian human group C rotavirus strains (Jajeri and Moduganari) were sequenced in this study. Comparative sequence analysis with other published human group C rotaviruses showed that the genes encoding the three structural proteins were remarkably conserved in primary structure with few mutations. The VP4 and VP7 genes from the two Nigerian strains were related more closely to each other than to those of other published strains, and formed a separate cluster on the phylogenetic tree. In contrast, it was of note that VP6 gene of strain Moduganari was related more closely to the Brazilian strain Belem than to the other Nigerian strain Jajeri. This is the first report of identification of human group C rotavirus in Nigeria and constitutes the first sequence data of human group C rotaviruses in the African continent.

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Section: Discussionmentioning

confidence: 51%

Detection of human group C rotaviruses in Nigeria and sequence analysis of their genes encoding VP4, VP6, and VP7 proteins

Adah

Wade

Oseto³

et al. 2001

Journal of Medical Virology

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“…Group C rotaviruses were first described in the diarrhoea stools of young children in the early 1980s, although the reports have always been limited in number (4)(5)(6)(7)(8)(9)(10)(11)(12). The identification of group C rotaviruses in Africa has also been limited with reports only from South Africa and Nigeria (13,14).…”

Section: Discussionmentioning

confidence: 99%

“…Group C rotaviruses, on the other hand, have been associated with either sporadic diarrhoeal illness or limited outbreaks in various settings Human group C rotaviruses have been described in several developed countries including Australia, USA, UK, Finland and Japan (4)(5)(6)(7)(8). In addition, the group C rotaviruses have been described in developing countries such as Latin America, India, China and Malaysia (9)(10)(11)(12). Furthermore, there have only been limited reports of the recovery of group C rotaviruses in humans in Africa (13,14).…”

Section: Introductionmentioning

confidence: 99%

Human group C rotaviruses identified in Kenya

Mwenda¹,

Peenze²,

Omollo³

et al. 2004

E Af Med Jrnl

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Background: Rotavirus is associated with acute infantile gastro-enteritis in infants and young children worldwide. Rotavirus is associated with the high cases of morbidity and mortality and it is estimated that up to 650,000 deaths in young children occur annually in the less developed countries. Approximately a quarter of these deaths occur in African children yet minimal data exist on the circulating rotavirus strains in Africa. Objective: To characterise the circulating rotavirus strains in Kenya. Design: A prospective study to investigate rotavirus infection in infants and young children with acute diarrhoea in different areas of Kenya. Between September 2001 and February 2002, 119 faecal specimens were collected from children aged between 1 and 60 months with acute infantile gastro-enteritis. Setting: Faecal samples were collected from clinics around Nairobi and its suburbs including Karen, Ngong, Ongata Rongai Subjects and Methods: Faecal samples were collected from 119 infants and young children with diarrhoea and were analysed by commercial ELISA and polyacrylamide gel electrophoresis (SDS-PAGE) to identify possible non-group A rotaviruses. Extraction of any potential rrotavirus double-stranded RNA from faeces amd characterisation by SDS-PAGE showed the presence of human group C rotaviruses. Results: Examination of these samples with a commercial ELISA assay for the presence of group A rotavirus antigen showed that 13 specimens (11%) were positive. An analysis of all stool specimens was performed by polyacrylamide gel electrophoresis to identify possible non-group A rotaviruses. Extraction of any potential rotavirus double-stranded RNA from faeces and characterisation by SDS-PAGE showed the presence of human group C rotaviruses. Conclusion: This is the first report of group C rotaviruses in Kenya. Further studies are underway to continue the surveillance of rotavirus strains in Kenya; as this information will be useful in planning rotavirus vaccine trials in Africa.

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“…Since then, they have been recognized in humans and animals, both in industrialized countries including Australia, United States, United Kingdom, Finland, and Japan and in developing countries or regions such as India, China, Malaysia, and Latin America (3,4,5,8,10,18,22,26,29,41). Thus, group C rotavirus strains are globally distributed and are thought to be one of the emerging pathogens in humans.…”

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confidence: 99%

Detection and Characterization of Human Group C Rotaviruses in Bangladesh

et al. 2005

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Group C rotaviruses were detected by reverse transcription-PCR in 14 (2.3%) of 611 group A rotavirusnegative stool specimens from the patients admitted to the International Centre for Diarrhoeal Disease Research, Bangladesh hospital, Dhaka, Bangladesh, during July to December 2003. The low rate of detection suggested that infection with group C rotaviruses was an uncommon cause of hospitalization due to gastroenteritis. In addition, coinfections with pathogenic enteric bacteria were frequently observed in group C rotavirus-infected patients. Nucleotide sequence comparison of the VP4, VP6, and VP7 genes revealed that the Bangladeshi group C rotaviruses were most similar to Nigerian group C rotavirus strains. Phylogenetic analysis suggested that all human group C rotaviruses, including the strains isolated in our study, clustered in a monophyletic branch, which was distantly related to the branch comprised of animal group C rotaviruses.

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Identification of a human group C rotavirus in Malaysia

Cited by 17 publications

References 27 publications

Detection of human group C rotaviruses in Nigeria and sequence analysis of their genes encoding VP4, VP6, and VP7 proteins

Detection of human group C rotaviruses in Nigeria and sequence analysis of their genes encoding VP4, VP6, and VP7 proteins

Human group C rotaviruses identified in Kenya

Detection and Characterization of Human Group C Rotaviruses in Bangladesh

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