Identification of a Brazil-Nut Allergen in Transgenic Soybeans

Nordlee, Julie A.; Taylor, Stephen L; Townsend, Jeffrey A.; Thomas, L. A.; Bush, Robert K.

doi:10.1056/nejm199603143341103

Cited by 594 publications

(296 citation statements)

References 18 publications

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“…In addition, it will be harder for people with food allergies to avoid consuming an offending food if proteins from that food are integrated into a food to which they are not allergic. For example, soybeans that were genetically engineered to contain proteins from Brazil nuts caused reactions in individuals who were allergic to Brazil nuts (103).…”

Section: Noted Thatmentioning

confidence: 99%

How sustainable agriculture can address the environmental and human health harms of industrial agriculture.

Horrigan

Lawrence

Walker

2002

Environ Health Perspect

907

546

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The industrial agriculture system consumes fossil fuel, water, and topsoil at unsustainable rates. It contributes to numerous forms of environmental degradation, including air and water pollution, soil depletion, diminishing biodiversity, and fish die-offs. Meat production contributes disproportionately to these problems, in part because feeding grain to livestock to produce meat--instead of feeding it directly to humans--involves a large energy loss, making animal agriculture more resource intensive than other forms of food production. The proliferation of factory-style animal agriculture creates environmental and public health concerns, including pollution from the high concentration of animal wastes and the extensive use of antibiotics, which may compromise their effectiveness in medical use. At the consumption end, animal fat is implicated in many of the chronic degenerative diseases that afflict industrial and newly industrializing societies, particularly cardiovascular disease and some cancers. In terms of human health, both affluent and poor countries could benefit from policies that more equitably distribute high-protein foods. The pesticides used heavily in industrial agriculture are associated with elevated cancer risks for workers and consumers and are coming under greater scrutiny for their links to endocrine disruption and reproductive dysfunction. In this article we outline the environmental and human health problems associated with current food production practices and discuss how these systems could be made more sustainable.

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Section: Noted Thatmentioning

confidence: 99%

How sustainable agriculture can address the environmental and human health harms of industrial agriculture.

Horrigan

Lawrence

Walker

2002

Environ Health Perspect

907

546

View full text Add to dashboard Cite

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“…An allergenic protein was also transferred and caused an allergic reaction in human volunteers. 13 This food was never approved for the market. The second, in 2005, involved experiments on mice in which a bean engineered to resist pea weevil triggered an immune reaction in the lungs of the animals.…”

Section: Safety Of Genetically Modified Foodsmentioning

confidence: 99%

Genetically modified foods and allergy

Lee

Leung

2017

Hong Kong Med J

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“…Si bien la manipulación genética es actual e importante, sólo afecta a un pequeño número de personas (5,6). Por el contrario, las alteraciones producidas en el ADN por la exposición ambiental a genotóxicos afectan a grandes poblaciones, incrementando la incidencia de malformaciones congénitas y cáncer(7-10).…”

Section: Desequilibrio En La Informaciónunclassified

Deterioro Genómico Y Manipulación Genética: Desequilibrio en La Prioridad De Las Agendas Públicas

González

Elío²

2007

Acta bioeth.

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Resumen: Se analiza el desequilibrio en el tratamiento de dos temas que atañen a la conservación de la integridad del genoma humano: las tecnologías de manipulación genética y el deterioro genómico provocado por la contaminación ambiental. Las carencias educativas, la falta de información asentada en los hechos y un manejo sensacionalista en los medios, entre otros factores, desajustan las agendas mediáticas con las necesidades públicas, lo que desemboca en una falta de conciencia ciudadana acerca de las verdaderas amenazas a las que está expuesto el material genético y los riesgos de salud que ello implica.Palabras clave: genotóxico, manipulación genética, deterioro genómico, bioética, toxicología ambiental, justicia ambiental GENOME DAMAGE AND GENETIC MANIPULATION. UNBALANCE IN PUBLIC POLICIES PRIORITYAbstract: Unbalance in the treatment of two topics related to the conservation of the human genome integrity is analyzed here: the technologies for genetic manipulation and genome damage due to environmental pollution. Lack of education and of information based on real facts, and the media sensationalist treatment, among other factors, provoke an unbalance between the media agenda and public needs. This leads to a lack of citizenship consciousness over the true threats that genetic material faces and the health risks that it involves.Keywords: genotoxic, genetic manipulation, genomic damage, bioethics, environmental toxicology, environment justice DETERIORIZAÇÃO GENÔMICA E MANIPULAÇÃO GENÉTICA. DESEQUILÍBRIO NA PRIORIDADE DAS AGENDAS PÚBLICASResumo: O presente texto analisa o desequilíbrio no tratamento de dois temas que dizem respeito à conservação da integridade do genoma humano: as tecnologias de manipulação genética e a deteriorização genômica provocada pela contaminação ambiental. As carências educativas, a falta de informação assentada nos fatos e um manejo sensacionalista dos meios, entre outros fatores, desajustam as agendas mediáticas com as necessidades públicas, o que desemboca numa falta de consciência cidadã em relação às verdadeiras ameaças à que se expôs o material genético e os riscos de saúde que isto implica.

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Identification of a Brazil-Nut Allergen in Transgenic Soybeans

Abstract: The 2S albumin is probably a major Brazil-nut allergen, and the transgenic soybeans analyzed in this study contain this protein. Our study show that an allergen from a food known to be allergenic can be transferred into another food by genetic engineering.

Cited by 594 publications

References 18 publications

How sustainable agriculture can address the environmental and human health harms of industrial agriculture.

How sustainable agriculture can address the environmental and human health harms of industrial agriculture.

Genetically modified foods and allergy

Deterioro Genómico Y Manipulación Genética: Desequilibrio en La Prioridad De Las Agendas Públicas

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