Identification, antifungal susceptibility and scanning electron microscopy of a keratinolytic strain of<i>Rhodotorula mucilaginosa</i>: a primary causative agent of onychomycosis

Cunha, Marcel; Santos, Luana Pereira Borba dos; Dornelas-Ribeiro, Marcos; Vermelho, Alane Beatriz; Rozental, Sônia

doi:10.1111/j.1574-695x.2009.00534.x

Cited by 21 publications

(24 citation statements)

References 43 publications

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“…The first case of onychomycosis caused by R. mucilaginosa was described by Cunha et al, which shows that these yeasts should also be considered as primary agents that can cause opportunistic onychomycosis [87]. The patient was immunocompetent, and the onychomycosis affected the nail of the hallux.…”

Section: Rhodotorula In Humansmentioning

confidence: 99%

Epidemiology ofRhodotorula: An Emerging Pathogen

Wirth

Goldani

2012

Interdisciplinary Perspectives on Infectious Diseases

226

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This is an updated paper focusing on the general epidemiological aspects of Rhodotorula in humans, animals, and the environment. Previously considered nonpathogenic, Rhodotorula species have emerged as opportunistic pathogens that have the ability to colonise and infect susceptible patients. Rhodotorula species are ubiquitous saprophytic yeasts that can be recovered from many environmental sources. Several authors describe the isolation of this fungus from different ecosystems, including sites with unfavourable conditions. Compared to R. mucilaginosa, R. glutinis and R. minuta are less frequently isolated from natural environments. Among the few references to the pathogenicity of Rhodotorula spp. in animals, there are several reports of an outbreak of skin infections in chickens and sea animals and lung infections and otitis in sheep and cattle. Most of the cases of infection due to Rhodotorula in humans were fungemia associated with central venous catheter (CVC) use. The most common underlying diseases included solid and haematologic malignancies in patients who were receiving corticosteroids and cytotoxic drugs, the presence of CVC, and the use of broad-spectrum antibiotics. Unlike fungemia, some of the other localised infections caused by Rhodotorula, including meningeal, skin, ocular, peritoneal, and prosthetic joint infections, are not necessarily linked to the use of CVCs or immunosuppression.

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Section: Rhodotorula In Humansmentioning

confidence: 99%

Epidemiology ofRhodotorula: An Emerging Pathogen

Wirth

Goldani

2012

Interdisciplinary Perspectives on Infectious Diseases

226

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“…(22,23) More recently, this microorganism has been implicated as a causative agent in onychomycosis. (24) …”

Section: Discusssionmentioning

confidence: 99%

Doença de Marchiafava-Bignami: uma rara entidade com prognóstico sombrio

Carrilho¹,

Santos²,

Piasecki³

et al. 2013

Rev. bras. ter. intensiva

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Marchiafava-Bignami disease is a rare affliction characterized by primary degeneration of the corpus callosum associated with chronic consumption of ethanol. The disease may occasionally occur in patients who are not alcoholics but are chronically malnourished. A complex deficiency of group B vitamins is the main etiopathogenic hypothesis, and many patients improve after the administration of these compounds. However, a good response is not always observed. The definitive diagnosis of Marchiafava-Bignami disease can be problematic and is based on features of neuroimaging studies, especially magnetic resonance imaging. Its treatment is still controversial and shows variable results. Because nutritional factors are implicated, as in Wernicke's encephalopathy, some authors claim that replacement of B vitamins is beneficial. The present article is a case report of a severe acute form of Marchiafava-Bignami disease in an alcohol-dependent male patient who improved after the administration of parenteral B vitamins. As a consequence of his neurological and immunologic conditions, he developed multiple pulmonary infections and had a protracted course in the intensive care unit. He eventually died of sepsis associated with an uncommon fungus, Rhodotorula mucilaginosa. The present article reports the clinical and neuroimaging data from this patient and contains a review of Marchiafava-Bignami disease and Rhodotorula infections in the intensive care unit.

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“…S. cerevisiae is fully accepted for human consumption and is the most common food grade yeast (Bekatorou et al, 2006). Contrary the presence of R. mucilaginosa in sorghum beer could be dangerous because it has been reported to cause Onychomycosis (Da Cunha et al, 2009;Jimoh et al, 2011). It was reported that certain yeasts involved in sorghum beer production were phenotypically different from reference strains (van der Aa Kühle et al, 2001).…”

Section: Discussionmentioning

confidence: 99%

Isolation and molecular identification of yeast strains from Rabil a starter of local fermented drink

Keita¹,

Somda²,

Savadogo³

et al. 2016

Afr. J. Biotechnol.

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Rabilé" is dried yeast harvested from Sorghum beer, used as a traditional starter culture but more especially as ingredient in sauce and food cooking in Burkina Faso. The present study aimed to isolate and identify indigenous yeast flora of "Rabilé". Standard microbiological process was carried out to value and isolate yeast in different samples of "Rabilé" coming from four localities of Burkina Faso. Phenotypical method and molecular method (PCR and RFLP) were used for yeast strains characterization and identification. The results showed that yeast counts ranged from 9.49 to 10.35 log cfu/g of "Rabilé". A total of twenty yeast strains were isolated. Based on phenotypical characters three genera were detected: Candida (40%), Saccharomyces (35%) and Rhodotorula (25%). Molecular identification revealed two specific strains among yeasts isolated as S. cerevisiae with a frequency of 35% and R. mucilaginosa with a frequency of 25%. This data highlights the diversity of indigenous yeast flora of "Rabilé".

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Identification, antifungal susceptibility and scanning electron microscopy of a keratinolytic strain ofRhodotorula mucilaginosa: a primary causative agent of onychomycosis

Cited by 21 publications

References 43 publications

Epidemiology ofRhodotorula: An Emerging Pathogen

Epidemiology ofRhodotorula: An Emerging Pathogen

Doença de Marchiafava-Bignami: uma rara entidade com prognóstico sombrio

Isolation and molecular identification of yeast strains from Rabil a starter of local fermented drink

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