“…After hybridization, the modified probe is detected by using antibodies, directed against guanosylacetylaminofluorene, and an immunoenzymatic technique. AAF-modified nucleic acids have been widely used for in situ [23,24], dot-blot [14,15,[25][26][27], Southern, colony and plaque hybridizations [15] as well as for the detection of PCR products [28]. The ability to label RNA and DNA, doublestranded as well as single-stranded nucleic acids, extends the applicability of the AAF method.…”