Ideational apraxia: A quantitative study

Renzi, Ennio De; Pieczuro, A; Vignolo, Luigi A.

doi:10.1016/0028-3932(68)90037-7

Cited by 257 publications

(96 citation statements)

References 10 publications

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“…All patients and subjects were right handed (Oldfield, 1971). Patients were divided into two groups depending on the presence or absence of apraxia as assessed by standard neuropsychological tests: tests of imitating meaningless (1) hand positions or (2) finger configurations (Goldenberg, 1996), (3) pantomiming the use of objects or actually using (4) single or (5) multiple objects (De Renzi et al, 1968;Hartmann et al, 2005) were used. Patients were classified as apraxic if they scored below the cutoff on at least one of these tests.…”

Section: Methodsmentioning

confidence: 99%

Apraxia Impairs Intentional Retrieval of Incidentally Acquired Motor Knowledge

Dovern¹,

Fink²,

Saliger³

et al. 2011

J. Neurosci.

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Apraxia caused by left hemispheric stroke typically impairs skilled sequential movements. After stroke, apraxic patients need to reacquire motor skills by motor learning. The current study assessed for the first time incidental motor sequence learning in apraxic patients. Forty-eight human subjects (henceforth called "patients") with left hemispheric stroke affecting the middle cerebral artery territory (18 with apraxia and 30 without apraxia) and 17 age-matched healthy controls were tested on a visuomanual serial reaction time task. Subjects performed four blocks consisting of repetitions of a complex six element sequence containing ambiguous pairwise transitions before a new and unfamiliar sequence was introduced in block 5. Reaction time (RT) disadvantages in this fifth block indicated incidental sequence-specific motor learning. The intentional retrieval of the learned motor knowledge was assessed subsequently with a free recall task. Voxel-based lesion-symptom mapping (VLSM) was performed to investigate for the first time the lesion correlates of deficits in learning and retrieving sequential motor knowledge. Despite generally prolonged RTs, apraxic patients showed sequence-specific motor learning as could be observed in nonapraxic patients and healthy controls. However, apraxic patients showed reduced intentional retrieval of the learned sequence. VLSM revealed that impaired intentional retrieval of motor sequence knowledge resulted from dorsal premotor cortex lesions. Apraxic patients showed a dissociation of preserved incidental motor (sequence) learning and deficient intentional retrieval of this incidentally learned motor knowledge. The data suggest that novel approaches for treating apraxia should focus on incidental motor learning, but that automatic rather than intentional retrieval strategies should be enforced.

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Section: Methodsmentioning

confidence: 99%

Apraxia Impairs Intentional Retrieval of Incidentally Acquired Motor Knowledge

Dovern¹,

Fink²,

Saliger³

et al. 2011

J. Neurosci.

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“…For instance, some researchers included impairment of single tool use in ideomotor apraxia, reserving the term ideational apraxia only for impairment of tool use involving plural items [1, 2, 3]. Others included impairment involving any tool use into the category of ideational apraxia [4, 5]. In this report, we would like to use the descriptive term of ‘apraxia of tool use’ for behavioral impairment involving tool use to avoid confusion.…”

Section: Introductionmentioning

confidence: 99%

Apraxia of Single Tool Use

Hayakawa¹,

Yamadori²,

Fujii³

et al. 2000

Eur Neurol

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We report a 72-year-old right-handed man who showed an ‘apraxia of tool use’ after a cerebral infarct in the territory of the left middle cerebral artery. His apraxia of tool use was characterized by a clear dissociation between the inability to use a single tool and the ability to use plural tools. Most of the errors occurred in selecting an appropriate target where a tool is expected to be applied. Detailed examinations confirmed that his conceptual knowledge of tool use was well preserved. Furthermore, when a target of a tool was provided as a cue, he used a single tool correctly. These results suggest that his inability to use a single tool originated from his inability to evoke a target image from an actual tool.

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“…While aphasia is primarily characterized by disturbance of language functions following brain injury, patients have been observed to also exhibit impairments in nonverbal domains, revealed by tasks such as associating pictures with corresponding objects (De Renzi, Pieczuro, & Vignolo, 1968), colors with pictures (De Renzi, Faglioni, Scotti, & Spinnler, 1972), and environmental sounds with pictures (e.g., Saygin, Dick, Wilson, Dronkers, & Bates, 2003a;Spinnler & Vignolo, 1966). In particular, aphasic patients' deficits in using and recognizing signs, gestures and pantomime have boy licking an invisible ice-cream cone) to the corresponding object (in this case, the ice-cream cone).…”

Section: Introductionmentioning

confidence: 99%

Action comprehension in aphasia: linguistic and non-linguistic deficits and their lesion correlates

et al. 2004

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We tested aphasic patients' comprehension of actions to examine processing deficits in the linguistic and non-linguistic domains and their lesion correlates. Twenty-nine left-hemisphere injured patients and 18 age-matched control subjects matched pictured actions (with the objects missing) or their linguistic equivalents (printed sentences with the object missing) to one of two visually-presented pictures of objects. Aphasic patients performed poorly not only in the linguistic domain but also in the non-linguistic domain. A subset of the patients, largely consisting of severe and non-fluent aphasics, showed a greater deficit in the linguistic domain compared with the non-linguistic domain and across the patient group, deficits in the linguistic and non-linguistic domains were not tightly correlated. Poor performance in pantomime interpretation was associated with lesions in the inferior frontal, premotor and motor cortex, a portion of somatosensory cortex, and the caudate, while poor reading comprehension of actions was associated with lesions around the anterior superior temporal lobe, the anterior insula and the anterior portion of the inferior parietal lobe. Lesion size did not correlate with deficits. The lesion results for pantomime interpretation deficits demonstrate that lesions in the frontal component of the human analog of the "mirror neuron system" are associated with deficits in non-linguistic action understanding. For reading comprehension deficits, the lesion correlates are brain areas known to be involved in linguistic tasks including sentence processing and speech articulation; the parietal lesion site may also correspond to a subpart of the human mirror neuron system. These results indicate that brain areas important for the production of language and action are also recruited in their comprehension. Similar findings have been reported in electrophysiological and neuroimaging studies. Our findings now also lend neuropsychological support to an embodied view of brain organization for action processing.

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Ideational apraxia: A quantitative study

Cited by 257 publications

References 10 publications

Apraxia Impairs Intentional Retrieval of Incidentally Acquired Motor Knowledge

Apraxia Impairs Intentional Retrieval of Incidentally Acquired Motor Knowledge

Apraxia of Single Tool Use

Action comprehension in aphasia: linguistic and non-linguistic deficits and their lesion correlates

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