2002
DOI: 10.1212/01.wnl.0000032493.83875.0b
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Ictal magnetic source imaging as a localizing tool in partial epilepsy

Abstract: Larger studies are necessary to confirm that ictal MEG recordings in patients with frequent or easily provoked neocortical seizures can contribute localizing information equivalent or superior to invasive EEG recording.

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Cited by 104 publications
(70 citation statements)
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“…The evidence supporting spike source localization to replace ICEEG has important implications for other technologies that attempt to do the same, namely, high-resolution EEG and spike-activated functional MRI source localization. Notable from this study and previously reported in the literature 13,20 is that the absence of using ictal source localization data did not appear to be problematic as long as results were interpreted in the context of all other tests of epilepsy localization, allowing interpretation of spikes unlikely to represent location of predominant seizure onsets. However, we must acknowledge that this study cannot yet help with determining the weighting of interictal MSI spike source localization regarding guiding with surgery.…”
Section: Magnetic Source Imaging and Intracranial Electroencephalogramentioning
confidence: 64%
“…The evidence supporting spike source localization to replace ICEEG has important implications for other technologies that attempt to do the same, namely, high-resolution EEG and spike-activated functional MRI source localization. Notable from this study and previously reported in the literature 13,20 is that the absence of using ictal source localization data did not appear to be problematic as long as results were interpreted in the context of all other tests of epilepsy localization, allowing interpretation of spikes unlikely to represent location of predominant seizure onsets. However, we must acknowledge that this study cannot yet help with determining the weighting of interictal MSI spike source localization regarding guiding with surgery.…”
Section: Magnetic Source Imaging and Intracranial Electroencephalogramentioning
confidence: 64%
“…Aún así, existen pocos estudios que describan la localización mediante MEG del inicio ictal 3,[5][6][7]12,14,15 , que es posible debido a que el artefacto de movimiento ocurre después del inicio de la crisis y habitualmente no interfiere en los datos utilizados en el cálculo de las fuentes de actividad magnética 5 . En nuestro caso se describe una crisis parcial registrada casualmente durante un registro MEG en un paciente mal controlado con dosis terapéuticas de anticonvulsivantes y con una alta frecuencia de crisis.…”
Section: Discussionunclassified
“…A pesar de que la capacidad de localización espacial se reduce por los movimientos de la cabeza durante la crisis generalizadas, bajo condiciones especiales se pueden obtener del trazado MEG datos sobre el inicio ictal 5 . Así la localización basada en datos ictales claramente definidos es considerada como superior a la basada en datos intercríticos 6 y puede aportar información equivalente o superior a la de los registros EEG invasivos 7 . En este artículo se describe la localización anatómica del inicio de una crisis parcial compleja y su propagación registrada casualmente durante la evaluación prequirúrgica mediante MEG de un paciente que presenta epilepsia farmacorresistente con crisis parciales complejas del lóbulo temporal.…”
unclassified
“…This has to be of particular concern with mesial temporal seizures where MEG is intrinsically limited to bias localization of propagated lateral temporal ictal activity. Still, in the few studies that have reported ictal MEG, case results were promising, revealing consistent localization with IC-EEG and good surgical outcomes [20,[32][33][34]. Notable also was the finding that ictal spikes agreed with interictal spike localization in most cases.…”
Section: Magnetoencephalography Accuracy In Epilepsy Localizationmentioning
confidence: 90%