Ichthyosis in a Nigerian Dwarf Goat

Abstract

Abstract:A 4-year-old Nigerian Dwarf goat presented with a long history of nonpruritic, scaly skin noticed since it was acquired at 3 weeks of age. Dermatologic examination revealed widespread large, white, nonadherent scales covering the entire skin. Histopathologic findings were characterized by noninflammatory compact diffuse orthokeratotic hyperkeratosis. Oral vitamin A therapy resulted in an approximate 85% reduction of the scaling with no reports of adverse effects. This is the first reported case of ichthyosis in the goat. Oral vitamin A may be beneficial for the management of caprine ichthyosis.

Ichthyosis fetalis in a cross‐bred lamb

“…Such therapies are impractical in livestock species because of the high costs of these treatments . In a case report, an adult Nigerian dwarf goat with a clinical diagnosis of ichthyosis was treated with oral vitamin A therapy that resulted in an approximately 85% reduction in scaling after three months of continuous treatment . In our cross‐bred lamb, initial therapy with antibiotics and skin moistening was effective in treating sepsis and the secondary bacterial infections of the skin wounds.…”

“…Ichthyosis congenita (IC) is a milder clinical form reported in Jersey, Pinzgauer, Holstein–Friesian and Chianina breeds . The form of ichthyosis described for the goat was likely IC . For sheep, to the best of the authors’ knowledge, none of the forms have been described.…”

“…The suggested pathogenesis includes an increase in hyperplasia of the stratum basale, increased epidermal turnover time, increased cell adhesion in the stratum corneum, failure of these cells to exfoliate normally and alterations in lipid metabolism . In domestic animals, ichthyosis has been reported in cattle, swine, dogs, chickens and a goat …”

“…1,4 In domestic animals, ichthyosis has been reported in cattle, swine, dogs, chickens and a goat. [1][2][3][5][6][7][8][9] Two congenital forms of ichthyosis are recognized in cattle. [1][2][3][6][7][8] The most severe form is ichthyosis fetalis (IF), also known as bovine harlequin fetus, and has been reported in Chianina, Holstein Friesian, brown Swiss, Norwegian red poll, Belgian white and red, and HanWoo calves.…”

“…1,2,6,7,10 The form of ichthyosis described for the goat was likely IC. 5 For sheep, to the best of the authors' knowledge, none of the forms have been described. Therefore, the aim of this paper is to describe the clinical, laboratory and pathological findings in a case of IF in a cross-bred lamb.…”