Iatrogenic Cushing's Syndrome After Intrapericardial Corticosteroid Therapy

Intrapericardial triamcinolone for acute pericarditis after electrophysiologic procedures

“…10 Adverse effects and complications reported in previous cases of intrapericardial corticosteroids include iatrogenic Cushing's syndrome and iatrogenic arteriovenous fistula of the mammary artery and vein. 12,13 The major limitation of this case series is the lack of complete followup data. The electronic medical records allowed for evaluation of each patient to determine if reentry into the same health system occurred.…”

Intrapericardial therapy and diagnosis

“…Human trials have begun, and should clarify the clinical contributions of these direct methods while always considering potential toxicities. For example, mild iatrogenic Cushing's syndrome has followed intrapericardial administration of usually nonabsorbable triamcinolone in humans [29]. Accordingly, despite uniform absence in animal studies, the possibility of adverse effects of even nitric oxide in a pericardial reservoir must be explored.…”

Cushing Syndrome Induced by Serial Occipital Nerve Blocks Containing Corticosteroids

“…The systemic administration of exogenous corticosteroids is probably the most common cause of Cushing syndrome. Local administration of corticosteroids, such as paraspinal injections for analgesia, 8 intradermal injection for skin disorders, 9 intrapericardial injections, 10 intraurethral injection for strictures, 11 and intra‐articular injections 12 can also induce Cushing syndrome. However, to our knowledge, this is the first case report of Cushing syndrome caused by serial occipital nerve blockade.…”