2014
DOI: 10.1155/2014/781493
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Iatrogenic Anetoderma of Prematurity: A Case Report and Review of the Literature

Abstract: Anetoderma is a skin disorder characterized by focal loss of elastic tissue in the mid dermis, resulting in localized areas of macular depressions or pouchlike herniations of skin. An iatrogenic form of anetoderma has been rarely described in extremely premature infants and has been related to the placement of monitoring devices on the patient skin. Because of the increasing survival of extremely premature infants, it is easy to foresee that the prevalence of anetoderma of prematurity will increase in the next… Show more

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Cited by 7 publications
(14 citation statements)
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“…At this point in gestation, the keratinization process of nails has already taken place and repeated contact with the fragile skin in the same area could potentially cause permanent damage. Immature skin is known to be prone to scar formation from minor trauma as evidenced by premature neonates who may develop scars from routine medical procedures, such as the placement of electrocardiographic leads . This hypothesis of toenail impingement on the skin during gestation may provide a simple explanation for otherwise unexplained SD in healthy infants.…”
Section: Discussionmentioning
confidence: 99%
“…At this point in gestation, the keratinization process of nails has already taken place and repeated contact with the fragile skin in the same area could potentially cause permanent damage. Immature skin is known to be prone to scar formation from minor trauma as evidenced by premature neonates who may develop scars from routine medical procedures, such as the placement of electrocardiographic leads . This hypothesis of toenail impingement on the skin during gestation may provide a simple explanation for otherwise unexplained SD in healthy infants.…”
Section: Discussionmentioning
confidence: 99%
“…In the primary form, lesions appear spontaneously on clinically normal skin, without any preceding dermatosis, and, despite its unclear pathogenesis, some authors report the association with autoimmune diseases . Familial cases are rare, with both autosomal dominant and recessive inheritance reported . Secondary anetoderma is preceded by inflammatory, infectious or neoplastic conditions and may be related to an abnormal repair mechanism of injured skin …”
Section: Discussionmentioning
confidence: 99%
“…Anetoderma ( anetos , Greek for slack), also known as macular atrophy, is a rare elastolytic disorder characterized by circumscribed areas of flaccid skin due to focal loss of dermal elastic tissue, resulting in normochromic or erythematous papules and plaques with a wrinkled and atrophic surface . Older lesions may form soft sack‐like projections, which yield on pressure .…”
Section: Introductionmentioning
confidence: 99%
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“…Secondary anetoderma is a reactive process linked to a known preceding inflammatory, infectious, autoimmune, or drug-induced condition. 3 On histopathology, both primary and secondary anetoderma are characterized by a loss of elastic tissue or elastin fibers in the superficial to mid dermis. 2 Anetoderma of prematurity was first described in 1996 by Prizant et al 4 in 9 extremely premature (24-29 weeks' gestation) infants in neonatal intensive care units (NICUs).…”
mentioning
confidence: 99%