I.V. paracetamol as an adjunct to patient-controlled epidural analgesia with levobupivacaine and fentanyl in labour: a randomized controlled study

Abstract

Clinical Trials Registry-India (http://ctri.nic.in/Clinicaltrials/login.php), trial registration number 2013/09/003968.

Interventions for the prevention or treatment of epidural-related maternal fever: a systematic review and meta-analysis

“…An additional four records were identified by searching the grey literature, and one final record was obtained by correspondence with a trial author (P. Steer, personal communication, 2021). Thus, a total of 42 records 11 , 12 , 13 , 14 , 15 , 51 , 52 , 53 , 54 , 55 , 56 , 57 , 58 , 59 , 60 , 61 , 62 , 63 , 64 , 65 , 66 , 67 , 68 , 69 , 70 , 71 , 72 , 73 , 74 , 75 , 76 , 77 , 78 , 79 , 80 , 81 , 82 , 83 , 84 , 85 , 86 , 87 – representing 34 studies and including a total 10 221 participants – are included in the review.…”

“… 72 Eight compared alternative methods of analgesia, 54 , 57 , 60 , 64 , 69 , 77 , 78 , 82 one evaluated additional epidural opioid, 65 two trials evaluated either warming the epidural solution 59 or using a heated neck warmer, 74 and two trials evaluated methods of acupuncture. 51 , 55 Three trials evaluated steroid 13 , 85 , 87 prophylaxis, two trials evaluated paracetamol 14 , 58 prophylaxis, and one trial evaluated antibiotic 15 prophylaxis. One trial evaluated both intravenous patient-controlled analgesia (PCA) remifentanil and prophylactic paracetamol.…”

“…51 , 55 , 76 , 83 , 87 Placebos were used by the trial evaluating prophylactic antibiotics, 15 two trials evaluating prophylactic steroids 13 , 85 and two trials evaluating prophylactic paracetamol. 14 , 58 …”

Microwave-Assisted Synthesis, Structural Characterization and Assessment of the Antibacterial Activity of Some New Aminopyridine, Pyrrolidine, Piperidine and Morpholine Acetamides

“…2-Chloro-N-(pyridin-3-yl)acetamide (19). Brown crystals, m.p., 196-198 • C; (Yield: 4.1 g, 83%); υ max [KBr]: 3500 cm −1 (N-H amide); 3040 cm −1 (C-H aromatic); 2981 cm −1 (C-H aliphatic); 1654 cm −1 (C=O amide); 1575 cm −1 (C=C); 1477 cm −1 (C-N); 740 cm −1 (C-Cl).…”

“…The compounds atorvastatin (2) [17], lidocaine (3) [18], paracetamol (4) [19], amoxicillin (5) [20], levobupivacaine (6) [21] are the most widely used drugs in medicine that contain the acetamide moiety 1 (Figure 1). Pyrrolidine, piperidine, morpholine, and piperazine are secondary amines that are very valuable saturated heterocyclic compounds because of their wide and diverse range of promising biological activities, such as antibacterial and anti-inflammatory activity [22][23][24][25][26].…”