<i>Treponema socranskii, Treponema denticola,</i> and <i>Porphyromonas gingivalis</i> Are Associated With Severity of Periodontal Tissue Destruction

Takeuchi, Yasuo; Umeda, Makoto; Sakamoto, Mitsuo; Benno, Yoshimi; Huang, Yi; Ishikawa, Isao

doi:10.1902/jop.2001.72.10.1354

Cited by 132 publications

(120 citation statements)

References 53 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…In the present study, the prevalence of P. gingivalis in the saliva samples of patients that had periodontal disease corroborates the reports by Dietrich and Takeuchi 19 , who demonstrated that P. gingivalis was a very virulent pathogen and that its detection must be used as a clinical indicator for periodontal disease.…”

Section: Discussionsupporting

confidence: 92%

See 1 more Smart Citation

Doença periodontal em portadoras de valvopatia durante a gravidez: estudo clínico e microbiológico

Ávila¹,

Timerman²,

Romito³

et al. 2011

Arq. Bras. Cardiol.

View full text Add to dashboard Cite

show abstract

Section: Discussionsupporting

confidence: 92%

“…Of this spectrum, possibly 10 to 20 species participate in the pathogenicity and periodontal destruction in periodontal disease 19 , with a prevalence of gram-negative anaerobic bacilli and among them, A. actinomycetemcomitans (Hacek group), P. gingivalis and P. intermedia, with a predominance in gingival samples 20 .…”

Section: Discussionmentioning

confidence: 99%

Doença periodontal em portadoras de valvopatia durante a gravidez: estudo clínico e microbiológico

Ávila¹,

Timerman²,

Romito³

et al. 2011

Arq. Bras. Cardiol.

View full text Add to dashboard Cite

show abstract

“…There is abundant evidence that the prevalence of major periodontal pathogens in oral specimens varies between individuals due to differences in their periodontal health status (3,4,12,19,20,27,30). In the present study, where the detection of selected pathogens was examined in a large, true population-based study population, this seemed to be the case for P. gingivalis, P. intermedia, T. denticola, and A. actinomycetemcomitans but, surprisingly, not for T. forsythensis.…”

Section: Discussionmentioning

confidence: 56%

Population-Based Study of Salivary Carriage of Periodontal Pathogens in Adults

Könönen¹,

et al. 2007

View full text Add to dashboard Cite

Large, general population-based data on carriage rates of periodontal pathogens hardly exist in the current literature. The objectives of the present study were to examine the salivary detection of Aggregatibacter (formerly Actinobacillus) actinomycetemcomitans, Campylobacter rectus, Porphyromonas gingivalis, Prevotella intermedia, Tannerella forsythensis, and Treponema denticola in a representative sample of the adult population living in southern Finland and to clarify which determinants are associated with the presence of these pathogens in saliva. 16S rRNA-based PCR methods with species-specific primers were employed to determine the presence of the six target bacteria in stimulated saliva samples, which were available from 1,294 subjects aged >30 years. The age group, gender, level of education, marital status, smoking history, number of teeth, and number of teeth with deepened pockets were included in the statistical analysis. In general, the carriage of periodontal pathogens was common, since at least one of the examined pathogens was found in 88.2% of the subjects. In descending order, the total detection rates were 56.9%, 38.2%, 35.4%, 31.3%, 20.0%, and 13.9% for T. forsythensis, T. denticola, P. gingivalis, C. rectus, A. actinomycetemcomitans, and P. intermedia, respectively. Age per se was strongly associated with the carriage of P. gingivalis (P ‫؍‬ 0.000), and the level of education with that of T. denticola (P ‫؍‬ 0.000). There was an association between the number of teeth with deepened pockets and carriage of P. gingivalis (P ‫؍‬ 0.000), P. intermedia (P ‫؍‬ 0.000), T. denticola (P ‫؍‬ 0.000), and A. actinomycetemcomitans (P ‫؍‬ 0.004). The data suggest that distinct species have a different carriage profile, depending on variables such as age, educational level, and periodontal status.Periodontitis is characterized by local infection and inflammation of tooth-supporting tissues, leading to various degrees of periodontal attachment loss in affected teeth. Different forms of periodontitis are multifactorial diseases where microorganisms present in dental biofilms are involved. Etiologic bacteria of periodontal diseases typically include gram-negative anaerobic bacteria: among those, Porphyromonas gingivalis, Prevotella intermedia, Tannerella forsythensis (formerly Bacteroides forsythus), and Treponema denticola are strictly anaerobic and Aggregatibacter (formerly Actinobacillus) actinomycetemcomitans and Campylobacter rectus are facultative/microaerobic (2,4,13,33). Several demographic and behavioral characteristics, such as race, age, gender, and smoking, as well as socioeconomic status, appear to be related to the prevalence of periodontitis, as shown in different populations worldwide (1). It may be expected that similar factors relate to the carriage pattern of periodontitis-associated microorganisms in similar ways as well. For example, the cumulative increase of periodontitis due to aging could be reflected by the increasing carriage of periodontal pathogen(s). As far as we know, natural car...

show abstract

“…Rezultat njihove aktivnosti je nastanak alkalne sredine i povišene temperature mikrosredine u kojoj se nalaze, što predstavlja bitan favorizujući faktor njihove aktivacije [10]. Parodontopatogeni mikroorganizmi mogu direkno ili indirekno prouzrokovati ili doprineti razvoju parodontopatije [12].…”

Section: Diskusijaunclassified

Detection and distribution of Actinobacillus actinomycetemcomitans in patients with aggressive parodontopathy

Staletovic¹,

Šehalić²,

Marjanović³

et al. 2016

Praxis Med

View full text Add to dashboard Cite

Parodontopatija je kompleksno oboljenje potpornog aparata zuba. Patološke promene koje se odvijaju u toku ove bolesti su destruktivne prirode i vode ka postepenom ili progresivnom obolevanju parodoncijuma i njegovoj anatomskoj i funkcionalnoj dezintegraciji. Cilj istraživanja bio je da se PCR metodom (eng. Polimerase Chain Reaction) utvrdi prisustvo i rasprostranjenost oralnog patogena Actinobacillus actinomycetemcomitans u subgingivalnom plaku kod pacijenata obolelih od agresivne parodontopatije, a zatim uporedi sa kvalitativno-kvantitativnim sastavom dentalnog plaka pacijenata obolelih od hronične parodontopatije. Ispitivanjem je obuhvaćeno 70 pacijenata prosečne starosti 45 godina. Utvrđivanje mikroorganizama u subgingivalnom plaku, određen je PCR metodom. U cilju postavljanja dijagnoze i određivanja stepena destrukcije parodontalnog tkiva, bili su korišćeni standardni epidemiološki kriterijumi: plak indeks (Silness-Lӧe), gingivalni indeks (Lӧe-Silness), SBI indeks (Mühleman-Son) i PDDž. Izuzetno visoka statistička značajnost prisustva A. actinomycetemcomitans-a dobijena je kod pacijenata sa agresivnom parodontopatijom. Prisustvo A. actinomycetemcomitans i P. gingivalis pokazalo je razliku u distribuciji kod pacijenata sa hroničnom i kod pacijenata sa agresivnom parodontopatijom. U našem uzorku A.a je detektovan u visokom procentu kod pacijenata mlađeg životnog doba sa dijagnozom agresivne parodontopatije. Veća učestalost A. actinomycetemcomitans-a u subgingivalnom plaku ima direktan uticaj na tok parodontopatije. Njegova detekcija može da bude koristan marker za utvrđivanje povećanog rizika za oboljevanje od agresivne parodontopatije kod pacijenata u mlađoj populaciji.Ključne reči: parodontopatija, subgingivalni plak, Actinobacillus actinomycetemcomitans, PCR UVODParodontopatija je kompleksno oboljenje potpornog aparata zuba. U toku bolesti patološkim procesom su zahvaćena sva parodontalna tkiva: gingiva, alveolarna kost, periodoncijum i cement korena zuba. Intezitet ispoljavanja kliničkih simptoma bolesti zavisi od tipa oboljenja, odnosno od aktivnosti patološkog procesa u parodoncijumu. Međutim, bez obzira na te faktore, etiopatogenetski circulus vitiosus koji vlada u parodoncijumu u toku aktivnosti patološkog procesa, uslovljava destrukciju svih parodontalnih tkiva što za posledicu ima anatomsku i funkcionalnu dezintegraciju parodoncijuma [1]. Epidemiološki podaci iz čitavog sveta ukazuju na izuzetnu rasprostranjenost gingivitisa i parodontopatije. Smatra se da su ovo, pored karijesa, najrasprostranjenija oboljenja ljudskog roda. Prema "Beogradskoj studiji", učestalost oboljenja parodoncijuma u domaćoj populaciji među osobama starijim od 18 godina je 84.6% i kreće se do 86.6% kod osoba starijih od 65 godina. Od ovog broja, blagi stepen destrukcije parodoncijuma ima 14.1% osoba, srednji 20.3%, dok su najteža oštećenja kod 10.4% ispitanika. Prema tome, ukupno 44.8% pregledanih osoba ima oštećenje dubljih tkiva parodoncijuma i formirane parodontalne džepove [2] .Američka parodontološka akademija je 1999 godi...

show abstract

Treponema socranskii, Treponema denticola, and Porphyromonas gingivalis Are Associated With Severity of Periodontal Tissue Destruction

Cited by 132 publications

References 53 publications

Doença periodontal em portadoras de valvopatia durante a gravidez: estudo clínico e microbiológico

Doença periodontal em portadoras de valvopatia durante a gravidez: estudo clínico e microbiológico

Population-Based Study of Salivary Carriage of Periodontal Pathogens in Adults

Detection and distribution of Actinobacillus actinomycetemcomitans in patients with aggressive parodontopathy

Contact Info

Product

Resources

About