The title compound, [Mn(C11H11N2O3)2(H2O)2], consists of discrete mononuclear complex molecules. The MnII atom is located on an inversion center and coordinated by two N atoms and two O atoms, each pair in a trans mode, from two 3-(2-hydroxyethyl)-2-methyl-4-oxopyrido[1,2-a]pyrimidin-9-olate ligands and by two water molecules. The coordination geometry around the MnII atom is slightly distorted octahedral. Molecules are linked by O—H⋯O hydrogen bonds into a three-dimensional network.