T2 measurement of the human myocardium using a T2‐prepared transient‐state trueFISP sequence

Huang, Tseng-Chieng; Liu, Yi-Jui; Stemmer, Alto; Poncelet, Brigitte P.

doi:10.1002/mrm.21208

Cited by 117 publications

(135 citation statements)

References 30 publications

(65 reference statements)

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“…Such T 2 value differences may occur due to slight changes related to B 0 and B 1 inhomogeneity, the relative accuracy of the fitting procedure, coil placement, among others. Furthermore, and consistent with prior reports that established T 2 -mapping at lower field strength (6,7), only 3 points were used for the monoexponential 2-parameter fit for the T 2 determination in this study. Although more points may result in an improved accuracy and robustness of the procedure, this remains to be investigated and has to be carefully balanced versus an increase in scanning time.…”

Section: Discussionmentioning

confidence: 88%

Free-Breathing 3 T Magnetic Resonance T2-Mapping of the Heart

Heeswijk

Feliciano

Bongard

et al. 2012

JACC: Cardiovascular Imaging

112

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Section: Discussionmentioning

confidence: 88%

Free-Breathing 3 T Magnetic Resonance T2-Mapping of the Heart

Heeswijk

Feliciano

Bongard

et al. 2012

JACC: Cardiovascular Imaging

112

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“…Recently, methods have been developed to reproducibly measure and map myocardial T 2 times (14). Clinical data using this promising technique, however, are not yet available.…”

Section: Cmr Techniques To Assess Tissue Pathologymentioning

confidence: 99%

Tissue Characterization of Acute Myocardial Infarction and Myocarditis by Cardiac Magnetic Resonance

Friedrich

2008

JACC: Cardiovascular Imaging

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Electrocardiograms, biomarkers, and ventricular function studies are diagnostic tools that are currently used to assess patients with acute myocardial disease. These tools are limited in their diagnostic accuracy and scope. Thus, for informed therapeutic decision making, tissue characterization may serve as a very important source of information in these initially regional diseases. Cardiac magnetic resonance (CMR) is becoming an important tool for phenotyping cardiac patients in vivo. Recent advances of CMR hardware and software as well as protocols have allowed for accurately visualizing tissue changes in patients with acute myocardial diseases. This is of special interest for acute myocardial infarction and acute myocarditis, because these entities may have a very similar clinical presentation and require immediate therapeutic decision making. Several CMR approaches can be combined in a comprehensive CMR examination, which provides information not only on ventricular size, morphology, and function, but also on the stage, degree, and extent of reversible and irreversible myocardial injury. Streamlined protocols allow such a CMR examination to be a time- and cost-efficient diagnostic tool, even in patients with acute disease. Current CMR approaches for visualizing tissue pathology in vivo are reviewed, examples are presented, and the potential role of CMR tissue characterization in patients with acute myocardial disease is discussed. The specific role of imaging the extent and regional distribution of myocardial edema and necrosis is discussed.

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“…A T2 preparation pulse is applied to impart T2 signal contrast, and a subsequent readout is performed by using a steady-state free precession (SSFP) sequence that has less sensitivity to turbo spin-echo artifacts (10,15,38). T2 mapping techniques have not yet received the same focus as T1 mapping techniques; thus, a comparison of diagnostic efficacy between the two techniques will be better served in future investigations.…”

Section: T2 Mapping Techniquementioning

confidence: 99%

Mapping the Future of Cardiac MR Imaging: Case-based Review of T1 and T2 Mapping Techniques

Hamlin¹,

Henry²,

Little³

et al. 2014

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Cardiac magnetic resonance (MR) imaging has grown over the past several decades into a validated, noninvasive diagnostic imaging tool with a pivotal role in cardiac morphologic and functional assessment and tissue characterization. With traditional cardiac MR imaging sequences, assessment of various pathologic conditions ranging from ischemic and nonischemic cardiomyopathy to cardiac involvement in systemic diseases (eg, amyloidosis and sarcoidosis) is possible; however, these sequences are most useful in focal myocardial disease, and image interpretation relies on subjective qualitative analysis of signal intensity. Newer T1 and T2 myocardial mapping techniques offer a quantitative assessment of the myocardium (by using T1 and T2 relaxation times), which can be helpful in focal disease, and demonstrate special utility in the evaluation of diffuse myocardial disease (eg, edema and fibrosis). Altered T1 and T2 relaxation times in disease states can be compared with published ranges of normal relaxation times in healthy patients. In conjunction with traditional cardiac MR imaging sequences, T1 and T2 mapping can limit the interpatient and interstudy variability that are common with qualitative analysis and may provide clinical markers for long-term follow-up.

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T₂ measurement of the human myocardium using a T₂‐prepared transient‐state trueFISP sequence

Cited by 117 publications

References 30 publications

Free-Breathing 3 T Magnetic Resonance T2-Mapping of the Heart

Free-Breathing 3 T Magnetic Resonance T2-Mapping of the Heart

Tissue Characterization of Acute Myocardial Infarction and Myocarditis by Cardiac Magnetic Resonance

Mapping the Future of Cardiac MR Imaging: Case-based Review of T1 and T2 Mapping Techniques

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