Stevia rebaudianaBertoni. Un potencial adyuvante en el tratamiento de la diabetes mellitus

Environmental cues induce changes of steviol glycosides contents and transcription of corresponding biosynthetic genes in Stevia rebaudiana

“…SGs are accumulated in leaves, and the content can be up to 30% of the leaf dry weight . The effects of the S. rebaudiana extract on anticariogenic, antineoplastic, antihypertensive, anti-inflammatory and antihyperglycemic were reported by many scientific literatures, and the antihyperglycemic effect is the most reported (Aranda-Gonzalez et al, 2014;Mohd-Radzman et al, 2013).…”

Stevia rebaudiana Bertoni bioactive effects: From in vivo to clinical trials towards future therapeutic approaches

“…In vivo and in vitro studies indicate that both stevia extract and stevioside have antihyperglycemic effects and their mechanisms of action are through gluconeogenesis suppression (stevia extract) and increased insulin secretion (stevia extract and stevioside); rebaudioside A increases insulin secretion exclusively in vitro and with high glucose concentrations (Aranda‐González, Segura‐Campos, Moguel‐Ordoñez, & Betancur‐Ancona, ). Other authors have stated similar results (Ruiz‐Ruiz et al, ).…”