<i>Staphylococcus aureus</i>Causing Tropical Pyomyositis, Amazon Basin, Peru

García, Coralith; Hallin, Marie; Deplano, Ariane; Denis, Olivier; Sihuincha, Moisés; Groot, Rozanne de; Gotuzzo, Eduardo; Jacobs, Jan

doi:10.3201/eid1901.120819

Cited by 22 publications

(17 citation statements)

References 13 publications

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“…The occurrence of PVL-producing strains does not exceed 2-5% among human routine clinical isolates in Europe, but can be higher in some other countries [111]. Associations with osteomyelitis and pyomyositis are now strongly suggested [117][118][119][120][121][122][123]. The locus encoding PVL is inside related bacteriophages [124][125][126][127]128].…”

Section: Panton-valentine Leukocidin (Pvl)mentioning

confidence: 96%

The staphylococcal alpha-toxin and leukotoxins

Prévost

Tawk

Zimmermann-Meisse

et al. 2015

The Comprehensive Sourcebook of Bacterial Protein Toxins

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Section: Panton-valentine Leukocidin (Pvl)mentioning

confidence: 96%

The staphylococcal alpha-toxin and leukotoxins

Prévost

Tawk

Zimmermann-Meisse

et al. 2015

The Comprehensive Sourcebook of Bacterial Protein Toxins

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“…Although the incidence of TP is still unclear in the tropics, it is an important cause of morbidity [26,27], including longer hospital stays (>10 days) [13,20]. The disease represents approximately 1% of all hospital admissions in the Amazonian region of Brazil or Peru [7,14]. Furthermore, it accounted for 4% (Gabon) to 27% (Benin) of S. aureus infections in Africa [28,29].…”

Section: Epidemiologymentioning

confidence: 99%

“…The amount of aspirated pus may reach 2000 ml in volume (Figure 1) [13]. Staphylococcus aureus, in particular methicillin‐susceptible S. aureus , is responsible for at least 40% and up to 100% (in the tropics) in some case reports [7‐8,14‐16]. Other bacterial species (i.e.…”

Section: Introductionmentioning

confidence: 99%

Tropical pyomyositis: an update

Shittu

Deinhardt‐Emmer

Nunes

et al. 2020

Tropical Med Int Health

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Tropical pyomyositis (TP) is a life-threatening bacterial infection of the skeletal muscle that occurs particularly among children, young adults and those with immunocompromised conditions. The appropriate diagnosis and treatment are often delayed due to its non-specific signs, leading to fatal consequences. Staphylococcus aureus, especially methicillin-susceptible S. aureus, is responsible for most TP cases. However, other bacteria (i.e. streptococci, Pseudomonas aeruginosa, Escherichia coli, Klebsiella spp., Candida spp., Mycobacterium spp.) have been reported. This narrative review provides an update on the epidemiology and clinical course of TP. A special focus is laid on the role of toxins (i.e. Panton-Valentine Leucocidin and a-toxin) in the pathogenesis of TP and their implication for the clinical management of infection.

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“…Staphylococcus aureus is the predominant pathogen, and certain staphylococcal genotypes may predominate [16]. Physical examination findings tend to be limited, but skin overlying affected muscle groups may have a “woody” feel.…”

Section: Epidemiology Of Ssti In the Usa Europe And Worldwidementioning

confidence: 99%

Diagnosis and management of skin and soft tissue infections in the intensive care unit: a review

2016

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Purpose: To review the salient features of the diagnosis and management of the most common skin and soft tissue infections (SSTI). This review focuses on severe SSTIs that require care in an intensive care unit (ICU), including toxic shock syndrome, myonecrosis/gas gangrene, and necrotizing fasciitis. Methods: Guidelines, expert opinion, and local institutional policies were reviewed. Results: Severe SSTIs are common and their management complex due to regional variation in predominant pathogens and antimicrobial resistance patterns, as well as variations in host immune responses. Unique aspects of care for SSTIs in the ICU are discussed, including the role of prosthetic devices, risk factors for bacteremia, and the need for surgical consultation. SSTI mimetics, the role of dermatologic consultation, and the unique features of SSTIs in immunocompromised hosts are also described. Conclusions: We provide recommendations for clinicians regarding optimal SSTI management in the ICU setting.

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Staphylococcus aureusCausing Tropical Pyomyositis, Amazon Basin, Peru

Cited by 22 publications

References 13 publications

The staphylococcal alpha-toxin and leukotoxins

The staphylococcal alpha-toxin and leukotoxins

Tropical pyomyositis: an update

Diagnosis and management of skin and soft tissue infections in the intensive care unit: a review

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