<i>Staphylococcus aureus</i>and hand eczema severity

Haslund, Poul; Bangsgaard, Nannie; Jarløv, Jens Otto; Skov, Lone; Skov, Robert; Agner, Tove

doi:10.1111/j.1365-2133.2009.09353.x

Cited by 61 publications

(72 citation statements)

References 30 publications

(60 reference statements)

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“…The severity of hand eczema correlates to the presence of Staphylococcus aureus [6], but the cause and effect relationship has not been clearly investigated. Knowledge on S. aureus colonization rates and epidemiology in hand eczema is limited [6,7]. Recent studies have however shown that more than 70 % of AD patients are colonized with S. aureus in skin lesions [8,9], often associated with clinical signs of secondary infection [10][11][12].…”

Section: Introductionmentioning

confidence: 99%

“…Sampling for bacterial culture from one or several sites from the hands is usually done with a cotton swab [6]. To obtain a more representative sample of the bacterial flora on the entire hand, the Bglove juice^method has been shown to give reliable and valid results [13].…”

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Staphylococcus aureus colonization related to severity of hand eczema

Mernelius

Carlsson

Henricson

et al. 2016

Eur J Clin Microbiol Infect Dis

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Knowledge on Staphylococcus aureus colonization rates and epidemiology in hand eczema is limited. The aim of this study was to clarify some of these issues. Samples were collected by the "glove juice" method from the hands of 59 patients with chronic hand eczema and 24 healthy individuals. Swab samples were taken from anterior nares and throat from 43 of the 59 patients and all healthy individuals. S. aureus were spa typed and analysed by DNA-microarray-based genotyping. The extent of the eczema was evaluated by the hand eczema extent score (HEES). The colonization rate was higher on the hands of hand eczema patients (69 %) compared to healthy individuals (21 %, p < 0.001). This was also seen for bacterial density (p = 0.002). Patients with severe hand eczema (HEES ≥ 13) had a significantly higher S. aureus density on their hands compared to those with milder eczema (HEES = 1 to 12, p = 0.004). There was no difference between patients and healthy individuals regarding colonization rates in anterior nares or throat. spa typing and DNA-microarray-based genotyping indicated certain types more prone to colonize eczematous skin. Simultaneous colonization, in one individual, with S. aureus of different types, was identified in 60-85 % of the study subjects. The colonization rate and density indicate a need for effective treatment of eczema and may have an impact on infection control in healthcare.

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Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Staphylococcus aureus colonization related to severity of hand eczema

Mernelius

Carlsson

Henricson

et al. 2016

Eur J Clin Microbiol Infect Dis

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“…In these countries the SA colonization rates were between 80% -100% [24,25]. However, SA colonisation rates in healthy Sri Lankan individuals (13%) were comparable to the rates reported in healthy European individuals (6-30%) [26]. Although, SA colonization rates were lower in AD patients in Sri Lanka, the presence of genes encoding SAg in SA isolates were similar to those from countries with a high prevalence.…”

Section: Discussionmentioning

confidence: 71%

Superantigen Profile of Staphylococcus Aureus Isolates from Patients with Atopic Dermatitis in Sri Lanka

PLR¹,

Malavige²,

Fernando³

et al. 2011

J Clin Exp Dermatol

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“…При этом обнаружена корреляция между степенью колонизации золотистым стафилококком и тяже-стью течения экземы. Таким образом, носительство S. aureus является значимым кофактором в патоге-незе экземы кистей [7].…”

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Etiopathogenetic Therapy of Inflammatory Dermatoses

Самцов

Хайрутдинов

Белоусова

2018

Vestnik dermatologii i venerologii

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Военно-медицинская академия им. С. М. Кирова Министерства обороны Российской Федерации 194044, Российская Федерация, Санкт-Петербург, ул. Академика Лебедева, д. 6При хронических дерматозах значительно увеличивается обсемененность кожи различными бакте-риями и грибами, которые могут оказывать негативное влияние на течение воспалительного процес-са. Крем «Кандидерм» является современным комбинированным топическим препаратом, оказыва-ющим противовоспалительное, антибактериальное и противогрибковое действие. Целью исследования была оценка эффективности, безопасности и переносимости крема «Канди-дерм» в терапии больных экземой и атопическим дерматитом. Материал и методы. Обследовано 37 пациентов с АД и 28 больных экземой. Применяли крем «Кан-дидерм» 2 раза в сутки, который наносили на пораженные участки кожи. До начала и на 14-е сутки терапии проводилось бактериологическое исследование микрофлоры кожи в области высыпаний. Результаты: на 14-е сутки у больных экземой ремиссия была достигнута у 17 (61 %) пациентов, зна-чительное улучшение -6 (21 %), улучшение -4 (14 %), отсутствие эффекта -1 (4 %); у больных АД ремиссия наблюдалась у 23 (62 %) пациентов, значительное улучшение -7 (19 %), улучшение -5 (14 %), отсутствие эффекта -2 (5 %). Выводы: высокая клиническая эффективность крема «Кандидерм» позволяет рекомендовать его для топической терапии больных нейроаллергодерматозами.

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Staphylococcus aureusand hand eczema severity

Abstract: Staphylococcus aureus was present on hands in almost half of all patients with HE, and was significantly related to severity of the disease. This association indicates that S. aureus could be an important cofactor for persistence of HE.

Cited by 61 publications

References 30 publications

Staphylococcus aureus colonization related to severity of hand eczema

Staphylococcus aureus colonization related to severity of hand eczema

Superantigen Profile of Staphylococcus Aureus Isolates from Patients with Atopic Dermatitis in Sri Lanka

Etiopathogenetic Therapy of Inflammatory Dermatoses

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