<i>Salmonella</i>-related urinary tract infection in an elderly patient

Klosterman, Scott

doi:10.1136/bcr-2014-204552

Cited by 5 publications

(6 citation statements)

References 8 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…were found to be involved in some UTI cases in this study. These bacteria are uncommon human pathogens and as a result, the infection cases are rare (29,30). The former is commonly acquired in humans through the ingestion of improperly preserved fish.…”

Section: Discussionmentioning

confidence: 99%

“…As regards Salmonella spp., this group of bacteria is generally responsible for typhoid fever. Many reports outlined their implication in UTIs, especially nontyphoidal strains (30,32). Similarly, this pathogen constitutes another health concern as Salmonella UTI which may complicate pyelonephritis, kidney failure, renal lithiasis, and chronic bacteriuria.…”

Section: Discussionmentioning

confidence: 99%

“…Similarly, this pathogen constitutes another health concern as Salmonella UTI which may complicate pyelonephritis, kidney failure, renal lithiasis, and chronic bacteriuria. Moreover, Salmonella UTI can worsen an enteric Salmonella infection (30).…”

Section: Discussionmentioning

confidence: 99%

See 2 more Smart Citations

Etiologic Profile and Sensitivity Pattern of Germs Responsible for Urinary Tract Infection Among Under-five Children in Douala, Cameroon: A Hospital-Based Study

Motse¹,

Ngaba²,

Koum³

et al. 2019

Avicenna J Clin Microbiol Infect

View full text Add to dashboard Cite

BackgroundUrinary tract infection (UTI) is usually defined as the presence of actively multiplying organisms in any part of the urinary tract such as kidneys, bladder, and urethra (1,2). Bacterial agents are mainly implicated as the causative germs of UTIs (3,4) which account for more than 95% of all cases (5). Viruses, parasites, and fungi may also be responsible for this type of infection, especially in immuno-compromised individuals (1,3). Each year, about 150 million urinary infection cases are recorded worldwide costing the world economy over six billion US dollars (5,6). According to some reports, several factors such as age, gender, race, and circumcision status are associated with an increased risk of UTI (1). The bulk of UTIinduced burden is concentrated on children, pregnant women, child-bearing women, and immunocompromised individuals (1,3).Similarly, evidence-based information regarding the epidemiology of UTIs is increasingly released but disseminated in the African continent. However, the existing studies evaluating the prevalence of UTI causative germs emphasized the significant predominance of Gram-negative bacteria with Escherichia coli, Staphylococcus aureus, and Klebsiella pneumoniae as the most prevalent germs (7-10).Young children represent one of the most social groups who are at the risk of UTI (1,3) which is a common and important public health problem since its symptoms in children may be subtle or non-specific making the diagnosis more complicated (11,12). In general, the symptoms in children may include fever, vomiting, diarrhoea, poor appetite, irritability, and the overall feeling of illness (4). When UTI is not early diagnosed, life-threatening complications such as sepsis and renal scarring may occur as a consequence. In addition, renal scarring is the most common cause of hypertension in later childhood and renal failure in adulthood (3,7,12).In developing countries particularly in resourceconstrained ones, the treatment of UTI heavily relies on an empiric or probabilistic approach (2,7,12) which owing to various reasons, may be initiated even before the availability of the final laboratory diagnostic test results (6). Accordingly, this increases the drug pressure which the uropathogens are exposed to and thus leads to the

show abstract

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Etiologic Profile and Sensitivity Pattern of Germs Responsible for Urinary Tract Infection Among Under-five Children in Douala, Cameroon: A Hospital-Based Study

Motse¹,

Ngaba²,

Koum³

et al. 2019

Avicenna J Clin Microbiol Infect

View full text Add to dashboard Cite

show abstract

“…(2) the risk of recurrent or chronic asymptomatic bacteriuria with shorter treatment regimens; and (3) the concern for antibiotic resistance in carriers despite normally appropriate treatment. 15 For doubly resistant strains (as in our patient), cefixime is recommended. With regard to the urinary carrier state, mechanical pathology of the urinary tract must be corrected.…”

Section: Discussionmentioning

confidence: 92%

Chronic urinary carrier state due to Salmonella Typhi causing urinary tract infection in an immunocompetent healthy woman

2018

View full text Add to dashboard Cite

Enteric fever caused by Salmonella Typhi is a global public health problem. With adequate treatment, most patients recover from the acute phase; however, 2-4% develop a chronic carrier state acting as reservoir of infection by continued shedding of bacteria in faeces and urine. Recovery of S. Typhi from urine is rare, even in endemic areas. The three main causes of bacteriuria arise following a recent episode of typhoid fever, in chronic carrier states involving the urinary system and occasionally following localised urinary tract infection (UTI) due to S. Typhi. Symptomatic Salmonella UTI is mostly encountered in an immunocompromised patient with some underlying structural abnormality involving the urinary tract. We report a case of symptomatic UTI caused by Salmonella Typhi in a 50-year-old immunocompetent woman in a chronic carrier state without any known urological abnormality.

show abstract

“…Two previous studies demonstrated low frequencies (1.4 to 2.8%) of Salmonella isolated from urine in comparison with other clinical samples (mainly enteric) in the São Paulo state, Brazil [14,15]. Despite this low occurrence, both old and recent scientific studies have reported the association of Salmonella in urine cultures with UTIs, mainly in immunocompromised and elderly hospitalized patients [16][17][18][19][20]. In the present study, we described 38 Salmonella isolates (all of them NTS) obtained from urine cultures of patients from seven different hospitals, five from Porto Alegre (the capital city) and two from two other important and populous cities of the Rio Grande do Sul state (Novo Hamburgo and Santa Maria).…”

mentioning

confidence: 98%

Salmonella isolates from urine cultures: serotypes and antimicrobial resistance in hospital settings

et al. 2019

View full text Add to dashboard Cite

This study investigated the serotypes and antimicrobial resistance of Salmonella isolates in urine cultures from 38 hospitalized patients. Nine serotypes were detected, and a large proportion was Typhimurium and Enteritidis. The strains presented resistance to 11 different antibiotics. Thirteen isolates (11 from serotype Typhimurium) exhibited multidrug resistance. Keywords Nontyphoid Salmonella. Urinary tract infections. Multidrug resistance Salmonella is an important pathogen causing approximately 550 million infections in the world per year [1]. Typhoid Salmonella (TS) serotypes (Typhi, Paratyphi A and B) are adapted to humans and cause typhoid fever, while nontyphoid Salmonella (NTS) serotypes infect a wide range of hosts, causing symptoms ranging from mild gastroenteritis to severe systemic infection. NTS has increasingly impacted human health, and it is responsible for approximately 93.8 million infections with 155,000 deaths per year [1, 2]. The clinical symptoms include diarrhea, fever, headache, and abdominal pain [3]. Infections by invasive NTS (iNTS) strains can also progress to severe life-threatening sepsis, a common cause of bacteremia in children and adults. The diversity in the clinical manifestations is explained by several factors, highlighting the occurrence of a large range of virulence factors in the bacterial strains [3, 4]. Urinary tract infections (UTIs) by Salmonella are infrequent in routine hospital practice and rarely reported in the scientific literature, although they may cause serious morbidity in immunocompromised and even in immunocompetent patients [5-8]. The present study describes the serotype identification and antimicrobial resistance of Salmonella isolates from urine cultures of hospitalized patients. A total of 38 Salmonella isolates were obtained from urine cultures in different hospitalized patients in Rio Grande do Sul state and sent to a public health laboratory (Laboratório Central do Rio Grande do Sul, LACEN-RS) from 2010 to 2015. Demographic data (such as hospital, city, and date of isolation; age and sex of the patients) were obtained in the clinical forms. The isolates were plated on Salmonella/ Shigella solid media, and presumptive Salmonella colonies were cultured in Triple Sugar Iron (TSI), Urea, Citrate, and Lysine Iron Agar (LIA) slants (Probac, São Paulo, Brazil). The isolates were submitted to aerobic incubation at 37°C for 24 h. Suspected Salmonella colonies were partially tested by agglutination with the main polyvalent O and H antisera (Probac, São Paulo, Brazil). Complete antigenic characterization was carried out for serotype identification in the National Reference Laboratory for Cholera and Enteric Diseases in the Institute Oswaldo Cruz (FIOCRUZ, Rio de Janeiro, RJ, Brazil) by the Kauffmann-White-Le Minor scheme [9]. All isolates were also submitted to DNA extraction and real-time polymerase chain reaction (PCR) targeting the invA

show abstract

Salmonella-related urinary tract infection in an elderly patient

Cited by 5 publications

References 8 publications

Etiologic Profile and Sensitivity Pattern of Germs Responsible for Urinary Tract Infection Among Under-five Children in Douala, Cameroon: A Hospital-Based Study

Etiologic Profile and Sensitivity Pattern of Germs Responsible for Urinary Tract Infection Among Under-five Children in Douala, Cameroon: A Hospital-Based Study

Chronic urinary carrier state due to Salmonella Typhi causing urinary tract infection in an immunocompetent healthy woman

Salmonella isolates from urine cultures: serotypes and antimicrobial resistance in hospital settings

Contact Info

Product

Resources

About