Reader. Lexington - D. C. Heath and Company, 1970

Multimodal P3 under different attentional states in mesial temporal lobe epilepsy

“…Although the generators of the P3 in humans are not known, studies from depth electrodes in epileptic patients suggest local generation of the P3 by mesial temporal lobe structures (limbic P3) (Halgren et al, 1986;McCarthy and Wood, 1987 2 ; Smith et al, 1990;Grunwald et al, 1995Grunwald et al, , 1998Grunwald et al, , 1999 and the temporoparietal junction (Knight et al, 1989). However, the contribution of subcortical (Onofrj et al, 1992a;Trinka et al, 2000a 3 ) and mesial temporal structures to scalp P3 is uncertain (Johnson 1986;Johnson and Fedio, 1988 4 ; Daruna et al, 1989;Rugg et al, 1991;Puce and Bladin, 1991 5 ; Onofrj et al, 1991Onofrj et al, , 1992bPolich and Squire, 1993 6 ; Nishitani et al, 1999;Trinka et al, 2000b 7,8 7,8 ). Nelson and coworkers demonstrated alterations of the scalp recorded P3 using a complex visual language discrimination task in patients with mesial temporal lobe epilepsy (mTLE), but lateralization of the seizure focus was not obtained in this study (Nelson et al, 1991).…”