<i>Nocardia</i>and nocardiosis

Beaman, Blaine L.; Boiron, P.; Beaman, L; Brownell, George H.; Schaal, K. P.; Gombert, Myles E.

doi:10.1080/02681219280001001

Cited by 59 publications

(69 citation statements)

References 59 publications

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“…Recently, it was suggested that these discrepant results may be due to the use of different methods for antimicrobial susceptibility testing (McNeil et al used a broth microdilution technique [383]). Alternatively, these discrepant results may reflect differences in the geographic origins of the particular isolates tested (42).…”

Section: Histopathologymentioning

confidence: 90%

“…Broad-spectrum cephalosporins such as cefotaxime have also been shown to be very active in vitro and successful in the therapy of experimental infections (570 (193,194). In addition, in other experimental studies that used antimicrobial combinations that have been shown to demonstrate synergy in vitro, imipenem-amikacin, imipenem-cefotaxime, and amikacin-cefotaxime were found to be efficacious (42,192,195). In a study of central nervous system nocardiosis, these combinations were also proven to be statistically superior to single-agent therapy (193 (23).…”

Section: Histopathologymentioning

confidence: 98%

“…It usually involves the lower limbs and is characterized by tumefaction, subcutaneous nodules, destructive granulomata, deformity, and discharging sinus tracts with intercommunicating channels that exude pus, often with macroscopically visible granules of various sizes and colors (12,52,70,104,226,293,326,527 (42). These infections most commonly affect patients in rural areas in Third World countries.…”

Section: Epidemiologic Aspects Of Infection In Humansmentioning

confidence: 99%

“…in laboratory studies or to have been proven successful in limited clinical case studies. Antimicrobial agents that may be of clinical benefit include broad-spectrum cephalosporins, fluoroquinolones (166,568), clindamycin, erythromycin, ampicillin, aminoglycosides (in particular, amikacin), tetracyclines (including minocycline), and imipenem (42,128). Broad-spectrum cephalosporins such as cefotaxime have also been shown to be very active in vitro and successful in the therapy of experimental infections (570 (193,194).…”

Section: Histopathologymentioning

confidence: 99%

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The medically important aerobic actinomycetes: epidemiology and microbiology

1994

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The aerobic actinomycetes are soil-inhabiting microorganisms that occur worldwide. In 1888, Nocard first recognized the pathogenic potential of this group of microorganisms. Since then, several aerobic actinomycetes have been a major source of interest for the commercial drug industry and have proved to be extremely useful microorganisms for producing novel antimicrobial agents. They have also been well known as potential veterinary pathogens affecting many different animal species. The medically important aerobic actinomycetes may cause significant morbidity and mortality, in particular in highly susceptible severely immunocompromised patients, including transplant recipients and patients infected with human immunodeficiency virus. However, the diagnosis of these infections may be difficult, and effective antimicrobial therapy may be complicated by antimicrobial resistance. The taxonomy of these microorganisms has been problematic. In recent revisions of their classification, new pathogenic species have been recognized. The development of additional and more reliable diagnostic tests and of a standardized method for antimicrobial susceptibility testing and the application of molecular techniques for the diagnosis and subtyping of these microorganisms are needed to better diagnose and treat infected patients and to identify effective control measures for these unusual pathogens. We review the epidemiology and microbiology of the major medically important aerobic actinomycetes.

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Section: Histopathologymentioning

confidence: 90%

Section: Histopathologymentioning

confidence: 98%

Section: Epidemiologic Aspects Of Infection In Humansmentioning

confidence: 99%

Section: Histopathologymentioning

confidence: 99%

See 2 more Smart Citations

The medically important aerobic actinomycetes: epidemiology and microbiology

1994

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“…Exudate, joint, CSF specimen and homogenized tissue specimens should be inoculated directly into media such as thioglycollate broth, trypticase soy broth or chopped-meat glucose broth. Serological methods including hemagglutination, precipitin, and complement-fixing antibody testing have a limited value because of a high degree of shared antigens and serological cross-reactivity among the heterogeneous pathogenic Nocardia species and other actinomycetes, especially Rhodococcus, Streptomyces, and Corynebacterium species 29 .…”

Section: Microbiologymentioning

confidence: 99%

Nocardiosis: Clinical and Pathological Aspects

Patil¹,

Nadkarni²,

Sharma³

2012

Histopathology - Reviews and Recent Advances

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Isolation of opportunistic fungi from bronchoalveolar lavage of compromised hosts in Isfahan, Iran

Shadzi

Chadeganipour

1996

Mycopathologia

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In this study, bronchoalveolar lavage (BAL) specimens from 247 immunocompromised patients were investigated for the incidence of opportunistic fungi. In the direct examination and culture of the specimens, 5 (2.02%) of filamentous fungi and 55 (22.26%) yeasts were isolated and identified as follows: Aspergillus fumigatus (2), A. terreus (1), A. nidulans (1), Mucor sp. (1), Candida albicans (29), C. glabrata (3), C. Parapsilosis (1), Trichosporon beigelii (1), Candida sp. (13) and unknown yeasts (8). In addition, one strain of Nocardia asteroides and two strains of Streptomyces sp. were isolated.

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Nocardiaand nocardiosis

Cited by 59 publications

References 59 publications

The medically important aerobic actinomycetes: epidemiology and microbiology

The medically important aerobic actinomycetes: epidemiology and microbiology

Nocardiosis: Clinical and Pathological Aspects

Isolation of opportunistic fungi from bronchoalveolar lavage of compromised hosts in Isfahan, Iran

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