“…Furthermore, some cis -elements in the mRNAs 3’-UTRs are also known to mediate the regulation of mRNA decay, such as PAT [29,30], ARE [31], iron-responsive element (IRE) [32], GRE [33], and MRE [34]. Many studies have demonstrated that the expression of TGFBR2 is modulated by MREs and their miRNAs in various cell types, such as miR-145 in vascular smooth muscle cells [35], miR-9-5p in hepatic stellate cells [36], miR-9 and miR-9-5p fibroblasts (HCFs) [6,37], miR-520e, miR-9-5p, and miR-135b in cancer cells [38,39,40]. Notably, miR-143 [23], miR-130a, miR-425, and miR-1306 [9] are known to target TGFBR2 in porcine GCs.…”