In vitroenzymatic response of Turkish native chicken “Gerze” to heavy metal exposure

Simple methanesulfonates are hydrolyzed by the sulfatase carbonic anhydrase activity

“…The purification of hCA isozymes was performed with a simple one step method by a Sepharose-4B-anilinesulfanilamide affinity column, as described earlier 7,8 . Inhibitory effects of compounds phenyl methanesulfonate (4), biphenyl-4-yl methanesulfonate (5), 1,4-phenylene dimethanesulfonate (6), phenol (7), biphenyl-4-ol (8), hydroquinone (9), pyrogallol (10), benzene-1,2,3-triyl trimethanesulfonate (11), catechol (12), 1,2-phenylene dimethanesulfonate (13), vanillin (14), 4-formyl-2-methoxyphenyl methanesulfonate (15), and guaiacol (16) on these different isoenzymes.…”

“…salicyclates and some of their derivatives [9][10][11] . Here we extend these earlier investigations to a series of phenolic compounds, some of which are widely used as antioxidant food additives or as drugs and which are reported to possess anticancer, anti-carcinogenic, antimutagenic, antibacterial, antiviral or anti-inflammatory activities [5][6][7][8][9][10][11] . Phenol 7, phenolic compounds 8-16 are widely used prodrugs or drugs.…”

“…Some of the isozymes are cytosolic (CA I, CA II, CA III, CA VII and CA XIII), two are mitochondrial (CA VA and CA VB), one is secreted (CA VI), and others are membrane bound (CA IV, CA IX, CA XII, CA XIV and CA XV [1][2][3][4][5][6][7][8] ). Many such CA isozymes involved in these processes are important therapeutic targets with the potential to be inhibited/ activated for the treatment of a range of disorders such as edema, glaucoma, obesity, cancer, epilepsy and osteoporosis [1][2][3][4][5][6][7][8] . Our groups recently investigated the interaction of CA I and II isozymes with several types of phenols, such as the simple phenol, hydroxy-/methoxysubstituted benzoic acids as well as di-/tri-methoxy benzenes, antioxidant bisphenols and several of its substituted derivatives, e.g.…”

Genetic diversity of village chickens in Central Black Sea Region and commercial chickens in Turkey by using microsatellite markers

“…Consciousness about conserving genetic reservoirs is of great importance because of the irreversible structure of these resources (9). Nevertheless, prioritization is crucial for conservation programs due to limited economic funds.…”

Characterization of carbonic anhydrase from Turkish native “Gerze” chicken and influences of metal ions on enzyme activity

“…Today, a limited number of Gerze chicken enthusiasts and governmental institutes as Lalahan Livestock Central Research Institution and Agricultural District Directorate of Gerze affiliated to the Turkish Ministry of Food, Agriculture and Animal Husbandry, conserve this genetic resource 15,16 . Consequently, there is a deep need to define existing chicken populations and to investigate their biochemical features so as to benefit people living in rural areas and scientists interested in this area 17 .…”