<i>In Vitro</i>Antimicrobial, Antioxidant, and Antispasmodic Activities and the Composition of the Essential Oil of<i>Origanum acutidens</i>(Hand.-Mazz.) Ietswaart

Göze, İsmihan; Alim, Ahmet; Çetinus, Şenay Akkuş; Çetin, Ali; Durmuş, Nedim; Ataş, Ahmet; Vural, Nilüfer

doi:10.1089/jmf.2009.0094

Cited by 18 publications

(9 citation statements)

References 21 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…One of their advantages is that they are natural reservoirs and laboratory experiments have shown no negative effects (14,15). In this research, the antibacterial activity of the O. vulgare essence was assessed against important pathogens by making some minor changes to the CLSI recommended agar dilution method which was originally developed for analyzing the conventional antimicrobial agents activities, so it could be used to analyze plant extracts and essential oils for their antimicrobial activities (16,17).…”

Section: Discussionmentioning

confidence: 99%

Antibacterial Effects of Origanum vulgare Essence Against Multidrug-Resistant Acinetobacter baumannii Isolated From Selected Hospitals of Tehran, Iran

Saghi

Bahador²,

Khaledi³

et al. 2015

Avicenna J Clin Microbiol Infect

View full text Add to dashboard Cite

Background: Infection due to Acinetobacter baumannii has become a significant challenge to modern healthcare systems. The rapid emergence and global dissemination of A. baumannii as a major nosocomial pathogen is remarkable and it demonstrates its successful adaptation to the 21st century hospital environment. Recent studies have discussed about essential oil of Origanum vulgare against a range of bacteria, including various species of Staphylococcus, Pseudomonas, Bacillus and Escherichia coli. Objectives: The present study aimed to investigate the inhibitory effects O. vulgare essence against multidrug-resistant (MDR) strains of A. baumannii from selected hospitals in Tehran, Iran. Materials and Methods: This oil was obtained using the hydrodistillation method and analyzed by gas chromatography mass spectrography (GC/MS). The antimicrobial activity against MDR isolates was achieved using disc diffusion method and macro-broth dilution assay. Results: Analysis of the essential oil revealed the presence of pulegone (68.59%) piperitone (7.8%), piperitenone (7.8%), 1, 8-cineole (1.3%), and carvacrol (1.6%) as the major components. The results showed a significant activity against MDR A. baumannii with inhibition zones and minimal inhibitory concentration values in the ranges of 7-15 mm and 20-35 µL/mL respectively. Conclusions: This investigation showed that the essence oil of O. vulgare had a potent antimicrobial activity against MDR A. baumannii. Further research is required to evaluate the practical values of therapeutic applications.

show abstract

Section: Discussionmentioning

confidence: 99%

Antibacterial Effects of Origanum vulgare Essence Against Multidrug-Resistant Acinetobacter baumannii Isolated From Selected Hospitals of Tehran, Iran

Saghi

Bahador²,

Khaledi³

et al. 2015

Avicenna J Clin Microbiol Infect

View full text Add to dashboard Cite

show abstract

“…Essential oil of Origanum acutidens contains high amounts of carvacrol. Carvacrol rates in some studies with Origanum acutidens are as follows: Kordali et al, (2008) determined 87.00% carvacrol; Tozlu et al, (2011) 86.99% carvacrol;Figueredo et al, (2012) 76.20% carvacrol;Cosge et al, (2009) 67.51% carvacrol; Baser et al, (1997) 66.25% carvacrol and Goze et al, (2010) determined 65.00% carvacrol. The main component of this oil is carvacrol followed by pcymene.…”

Section: Content and Yield Of Essential Oilmentioning

confidence: 99%

Areas of Utilization of Orıganum acutidens (HAND.-MAZZ.) Ietswaart and Carvacrol

Karagöz¹,

Karagöz²

2019

Int.J.Curr.Res.Aca.Rev.

View full text Add to dashboard Cite

Article InfoOriganum acutidens (Hand.-Mazz.) Ietswaart is an endemic plant growing in the eastern part of Turkey. Origanum acutidens, rich in rosmarinic acid, has a high antioxidant effect. The essential oil of this plant is rich in carvacrol. The plant has chemotypes containing up to 90% carvacrol. Carvacrol also has a comprehensive range of uses from health to food. According to results obtained from previous studies, carvacrol has a lethal effect against some cancer cells. Furthermore, carvacrol has antifungal and antibacterial effects and it is lethal for some agriculturally harmful insect species. In this study, we have compiled the details of various research findings related to the morphology, natural distribution and synonymous of Origanum acutidens, its karyological and histological features, its content and yield of essential oil and its pharmacological property and the effects of carvacrol based on an exhaustive literature review. Such knowledge could contribute to the design of new and more effective technologies for the increased use and in the number of plant-based drugs for plant and human health. Using alternative and integrative strategies such as phytochemicals against harmful insect families, bacteria and fungi in agricultural areas and storage conditions are among current necessities. In addition, this review may contribute to provide a new and additional perspective on cancer treatment by combining the finding that the carvacrol in the essential oil of Origanum acutidensis effective against cancer cells.

show abstract

“…O. acutidens and O. rotundifolium. Chemical profile [19][20][21][22] and insecticidal [23][24][25][26][27][28][29], antioxidant [30][31][32][33], antimicrobial and antibacterial [34][35][36] activities of the essential oils and some extracts were studied. It has been reported that essential oil of O. acutidens was found to be insecticidal due to its high concentration of carvacrol.…”

Section: Introductionmentioning

confidence: 99%

Screening of Chemical Composition, Antioxidant and Anticholinesterase Activity of Section Brevifilamentum of Origanum (L.) Species

Yilmaz¹,

Çarıkçı²,

Kılıç³

et al. 2017

Rec.Nat.Prod.

View full text Add to dashboard Cite

Brevifilamentum were analyzed for their essential oil and phenolic components. For the essential oil analyses, GC-MS and GC-FID were used. Phenolic contents of the aerial parts of the chloroform, acetone, and methanol extracts were analyzed using LC-MS/MS. Antioxidant activity of the species was investigated by three methods; DPPH free radical scavenging activity, β-carotene linoleic acid assays and CUPRAC assays. Also, acetyl and butyrylcholinesterase inhibition of the extracts were investigated. While the essential oil contents of the section Brevifilamentum showed difference in chemotype, the phenolic contents were found to be coumaric acids and derivatives. These groups were the most abundant components of the extracts. Especially rosmarinic acid was detected in high amounts in acetone and methanol extracts. OA had the best activity both in antioxidant and anticholinesterase assays.

show abstract

In VitroAntimicrobial, Antioxidant, and Antispasmodic Activities and the Composition of the Essential Oil ofOriganum acutidens(Hand.-Mazz.) Ietswaart

Cited by 18 publications

References 21 publications

Antibacterial Effects of Origanum vulgare Essence Against Multidrug-Resistant Acinetobacter baumannii Isolated From Selected Hospitals of Tehran, Iran

Antibacterial Effects of Origanum vulgare Essence Against Multidrug-Resistant Acinetobacter baumannii Isolated From Selected Hospitals of Tehran, Iran

Areas of Utilization of Orıganum acutidens (HAND.-MAZZ.) Ietswaart and Carvacrol

Screening of Chemical Composition, Antioxidant and Anticholinesterase Activity of Section Brevifilamentum of Origanum (L.) Species

Contact Info

Product

Resources

About