<i>In ovo</i> injection with glycerol and insulin-like growth factor (IGF-I): hatchability, intestinal morphometry, performance, and carcass characteristics of broilers

Neves, Danusa Gebin das; Retes, Pâmela Lacombe; Alves, Victória Veiga; Pereira, Rani Silva Guedes; Bueno, Yanka Do Couto; Alvarenga, Renata Ribeiro; Zangerônimo, Márcio Gilberto

doi:10.1080/1745039x.2020.1747377

Cited by 7 publications

(3 citation statements)

References 31 publications

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“…It was previously observed that increasing dietary LC concentrations in chicken diets enhanced plasma IGF-I concentrations ( El-Saway et al, 2022 ). Investigators claim that IGF-1 in various physiological forms plays a crucial role in cell proliferation and organ development ( Neves et al, 2020 ). We envision that the improvement in villus condition is linked to the increased level of IGF-1.…”

Section: Discussionmentioning

confidence: 99%

The effects of L-carnitine-loaded solid lipid nanoparticles on performance, antioxidant parameters, and expression of genes associated with cholesterol metabolism in laying hens

Eskandani¹,

Navidshad²,

Eskandani³

et al. 2022

Poultry Science

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Section: Discussionmentioning

confidence: 99%

The effects of L-carnitine-loaded solid lipid nanoparticles on performance, antioxidant parameters, and expression of genes associated with cholesterol metabolism in laying hens

Eskandani¹,

Navidshad²,

Eskandani³

et al. 2022

Poultry Science

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“…2) Losses in productivity from high morbidity and mortality rates during the first week post-hatch is also a significant economic burden to the poultry industry ( Noble and Cocchi, 1990 ; Wilson, 1991 ; Xin et al, 1994 ; Peebles et al, 2004 ). Avenues to optimize embryonic-to-neonatal transition, including the use of in ovo nutrient injection strategies ( Kadam et al, 2013 ; Peebles, 2018 ; Neves et al, 2020 ), early post-hatch dietary modifications ( Jha et al, 2019 ; Ravindran and Abdollahi, 2021 ) etc., are being investigated to optimize this critical transition of the embryo to the neonate. In summary, isolated hepatocytes from embryonic and neonatal chicken can be a reliable metabolic model to investigate the optimal remodeling of mitochondrial metabolism and its synergy to accommodate rapid rates of lipogenesis, while avoiding mechanisms promoting hepatocellular stress.…”

Section: Discussionmentioning

confidence: 99%

Remodeling of Hepatocyte Mitochondrial Metabolism and De Novo Lipogenesis During the Embryonic-to-Neonatal Transition in Chickens

et al. 2022

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Embryonic-to-neonatal development in chicken is characterized by high rates of lipid oxidation in the late-term embryonic liver and high rates of de novo lipogenesis in the neonatal liver. This rapid remodeling of hepatic mitochondrial and cytoplasmic networks occurs without symptoms of hepatocellular stress. Our objective was to characterize the metabolic phenotype of the embryonic and neonatal liver and explore whether these metabolic signatures are preserved in primary cultured hepatocytes. Plasma and liver metabolites were profiled using mass spectrometry based metabolomics on embryonic day 18 (ed18) and neonatal day 3 (nd3). Hepatocytes from ed18 and nd3 were isolated and cultured, and treated with insulin, glucagon, growth hormone and corticosterone to define hormonal responsiveness and determine their impacts on mitochondrial metabolism and lipogenesis. Metabolic profiling illustrated the clear transition from the embryonic liver relying on lipid oxidation to the neonatal liver upregulating de novo lipogenesis. This metabolic phenotype was conserved in the isolated hepatocytes from the embryos and the neonates. Cultured hepatocytes from the neonatal liver also maintained a robust response to insulin and glucagon, as evidenced by their contradictory effects on lipid oxidation and lipogenesis. In summary, primary hepatocytes from the embryonic and neonatal chicken could be a valuable tool to investigate mechanisms regulating hepatic mitochondrial metabolism and de novo lipogenesis.

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“…Effect on Hatchability * Positive Negative Non-Existent [78] Glycerol x Insulin-like growth factor [79] Zinc oxide nanoparticles x [80] Folic acid x Glucose [81] Ascorbic acid x Arginine [82] Bifidobacterium bifidum x x Bifidobacterium longum [83] Leucine…”

Section: Study Productmentioning

confidence: 99%

Bibliographical Mapping of Research into the Relationship between In Ovo Injection Practice and Hatchability in Poultry

Oliveira

Pimentel

Salgado

et al. 2023

Veterinary Sciences

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Recent advances in poultry practice have produced new tools enabling the poultry industry to increase productivity. Aiming at increasing production quality, varying protocols of in ovo injection facilitate the introduction of exogenous substances into the egg to complement the nutrients that support embryonic development up to hatching, which are already available in the internal and external compartments. Due to embryonic sensitivity, adding any substance into the egg can be either advantageous or disadvantageous for embryonic survival and can influence hatch rates. Thus, understanding the relationship between poultry practices and production rates is the first step towards successful commercial application. This review aims to assess the influence on hatch rates of injecting different substances in ovo, including effects on embryo and chick health parameters where these are reported. Bibliographic mappings of co-authorship of citations, co-occurrence of keywords, and bibliographic coupling based on the in ovo injection technique and hatchability parameters were also performed. Using the Scopus database, 242 papers were retrieved, reviewed, and submitted for bibliographic mapping using the VOSviewer® software. This review provides a broad overview of just over 38 years’ research on the subject, revealing that studies have significantly increased and peaked in 2020, being produced primarily by US researchers and published primarily in the journal Poultry Science. It also reveals that despite negative reports relating to some substances in the embryo, in ovo delivery of substances may possibly change the poultry industry for the better in terms of production rates (hatchability) and/or poultry health.

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In ovo injection with glycerol and insulin-like growth factor (IGF-I): hatchability, intestinal morphometry, performance, and carcass characteristics of broilers

Cited by 7 publications

References 31 publications

The effects of L-carnitine-loaded solid lipid nanoparticles on performance, antioxidant parameters, and expression of genes associated with cholesterol metabolism in laying hens

The effects of L-carnitine-loaded solid lipid nanoparticles on performance, antioxidant parameters, and expression of genes associated with cholesterol metabolism in laying hens

Remodeling of Hepatocyte Mitochondrial Metabolism and De Novo Lipogenesis During the Embryonic-to-Neonatal Transition in Chickens

Bibliographical Mapping of Research into the Relationship between In Ovo Injection Practice and Hatchability in Poultry

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