Helicobacter pylori and other factors in recurrent aphthous stomatitis: A cross‐sectional study

Abstract

Recurrent aphthous stomatitis (RAS) is the most prevalent oral lesion in the mouth (Akintoye & Greenberg, 2005). It is important for human health due to the associated pain and compromised quality of life (Brocklehurst et al., 2012). The etiology of this condition remains unclear (Edgar et al., 2017), despite studies that have evaluated the possible association of RAS with a large range of risk factors.Smoking appears as a protective factor, while young age and female gender are reported risk factors (Tüzün et al., 2000).The association of Helicobacter pylori with RAS has been evaluated. Beyond the stomach, where this bacterium is typically found,

Recurrent Aphthous Stomatitis – An Overview

“…Interestingly, in patients with RAS after eradication of H. pylori, there is a significant reduction in the number of aphthae which can be explained as a product of increased levels of vitamin B12 (37). However, other studies shown contrary results where patients positive on H. Pylori had a lower RAS prevalence than H. Pylori negative patients (38).…”

Oral mucosal diseases and psychosocial factors: progress in related neurobiological mechanisms

“… 6 One cross-sectional study that evaluated the clinical and demographic factors of RAU found that the condition was related to anxiety but not depression. 7 Conversely, by evaluating the relationship between salivary cortisol levels and anxiety and depression in patients with RAU, other researchers found RAU to be related to depression but not anxiety. 8 In another study, no correlation was found between RAU and stress, anxiety, and depression.…”