<i>Helcococcus ovis</i> isolated from a goat with purulent bronchopneumonia and pulmonary abscesses

García, Alfredo; Risco, David; Benítez, José Manuel; Martínez, R.; Garcı́a, Waldo; Cuesta, Jesús de Pedro; Gómez, L.; Sánchez, Sergio

doi:10.1177/1040638711425950

Cited by 10 publications

(8 citation statements)

References 7 publications

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“…The presence of thrombus associated with Gram-positive colony, histopathologic pattern, diffuse and widely distributed emboli in lungs, and the presence of endocarditis in the right side of the heart support the statement that pneumonia was due to thromboembolism. Our findings contrast with the ones in ZHANG et al (2009) and GARCÍA et al (2012) were in sheep and goat, respectively, described bronchopneumonia caused by H. ovis. We believed that our report and the other two reports described above had a different route of infection.…”

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confidence: 99%

Valvular endocarditis associated with Helcococcus ovis in a cow in Southern Brazil

et al. 2020

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A 4-year-old cow with a history of breathing difficulty, progressive weight loss, and muffled heart sound was treated for a period of two weeks, but died and underwent necropsy examination. Macroscopic examination revealed heart with vegetative proliferative lesion firmly adhered to pulmonary valve, lungs with marked consolidation, and the presence of thrombus in vessels. There were grade II ulcers in abomasal mucosa associated to blood clots. Microscopic examination revealed marked thickening of the pulmonary valve due to the proliferation of fibrous connective tissue, inflammatory neutrophil infiltration, fibrin deposition, and a significant number of coccoid basophilic bacteria. Septic thromboemboli were present in the large and small pulmonary blood vessels suggestive of embolic pneumonia. The bacterial culture of the valve showed growth of small, nonhemolytic colonies that demonstrated satellitism to coagulase-negative staphylococci contaminating colonies, which were subjected to 16S gene sequencing and were compatible with Helcococcus ovis in GenBank. This was the first report of H. ovis endocarditis in cattle in South America.

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Valvular endocarditis associated with Helcococcus ovis in a cow in Southern Brazil

et al. 2020

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“…This phenomenon is lost when H. ovis is subcultured. H. ovis is an infrequent cause of pneumonia, lung abscesses, and infective endocarditis among ruminants (23,24,25) but has never been reported to cause human disease. Thus, satellitism and pyridoxal dependence may be phenomena that are demonstrated by organisms of the Helcococcus genus in nutritionally abundant environmental milieus such as areas of necrosis with extensive tissue destruction, as in this patient with an erosive cholesteatoma.…”

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confidence: 99%

First Report of Brain Abscess Caused by a Satelliting Phenotypic Variant of Helcococcus kunzii

2014

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Helcococcus kunzii was isolated from a brain abscess in a diabetic patient with cholesteatoma and demonstrated satellitism around Staphylococcus aureus in culture. This is the first reported case of severe central nervous system infection due to H. kunzii and the first description of a satelliting phenotypic variant of this organism. CASE REPORTA n 83-year-old man was admitted with a worsening right earache and fever for 10 days. He had a background history of hypertension, diabetes mellitus, and prostate cancer and was on androgen blockade therapy. On admission, he had a temperature of 37.2°C and a fluctuating consciousness level. Otoscopic examination revealed an inflamed outer ear canal. Blood tests showed leukocytosis (13.93 ϫ 10 9 /liter) with neutrophilia (12.19 ϫ 10 9 / liter). Liver and renal function test results were unremarkable. Contrast-enhanced computed tomography scans of the head showed a right-sided cholesteatoma with abscess formation in the mastoid cavity. There was no definite evidence of intracranial extension. Excision of the cholesteatoma and mastoidectomy were performed. Histology showed the presence of keratinized squamous metaplasia consistent with the preoperative diagnosis of cholesteatoma. Cultures of pus swabs obtained from the mastoid abscess were negative for bacterial and fungal growth.In view of the severe clinical infection with systemic upset, the head and neck surgeons in charge started the patient on intravenous ceftriaxone at 2 g every 12 h and intravenous metronidazole at 500 mg every 8 h for broad-spectrum coverage of Gram-negative pathogens, methicillin-sensitive Staphylococcus aureus, and anaerobes. Antipseudomonal coverage was to be added if the patient's condition did not improve. After 2 weeks of intravenous antibiotics, he showed clinical improvement and was switched to oral amoxicillin-clavulanate at 1 g twice daily. However, he developed generalized tonic-clonic convulsions and a high fever 3 weeks after the operation. Reassessment by computed tomography scans of the brain with contrast enhancement showed a right temporal brain abscess (Fig. 1). The abscess was drained surgically. Intravenous ceftriaxone at 2 g every 12 h and intravenous metronidazole at 500 mg every 8 h were restarted. In addition, intravenous vancomycin at 500 mg every 12 h (dose adjusted for estimated creatinine clearance) was commenced in view of breakthrough abscess formation despite previous broad-spectrum beta-lactam antibiotic use. Empirical local amikacin instillation was used to irrigate the abscess cavity through the abscess drain as described in the literature (1, 2). The patient's neurological status improved with no further seizure episodes. In view of the clinical improvement and the results of in vitro antimicrobial susceptibility testing of the bacterial isolate obtained from the brain abscess drainage at the second operation, he was kept on a regimen of ceftriaxone, vancomycin, and metronidazole. Local amikacin instillation through the abscess drain was discontinued. Subsequent c...

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“…To date, four species have been described: Helcococcus kunzii (1993) (1), Helcococcus ovis (1999) (3), Helcococcus sueciensis (2004) (4), and Helcococcus seattlensis (2014) (5). H. ovis has been described from different animals but never from humans (3,(6)(7)(8)(9)(10)(11). H. sueciensis has been isolated only in humans from two wound infections and one bacteremia infection (4,5).…”

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Identification and Clinical Significance of Helcococcus kunzii in Human Samples

Vergne¹,

Guérin²,

Lienhard³

et al. 2015

J Clin Microbiol

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Helcococcus ovis isolated from a goat with purulent bronchopneumonia and pulmonary abscesses

Cited by 10 publications

References 7 publications

Valvular endocarditis associated with Helcococcus ovis in a cow in Southern Brazil

Valvular endocarditis associated with Helcococcus ovis in a cow in Southern Brazil

First Report of Brain Abscess Caused by a Satelliting Phenotypic Variant of Helcococcus kunzii

Identification and Clinical Significance of Helcococcus kunzii in Human Samples

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