<i>Haemophilus parainfluenzae</i>endocarditis with systemic embolisation following maxillary sinusitis

Cortes, M.; Teixeira, Vítor; Rego, F

doi:10.1136/bcr-2016-216473

Cited by 4 publications

(3 citation statements)

References 11 publications

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“…3,8 Our patient did not complain of any oropharyngeal or upper respiratory tract symptoms; however, he was found by CT scan to have maxillary sinusitis, which has been associated with the development of H parainfluenzae endocarditis with cerebral emboli. 10 Additionally, our case exhibited several relatively unique features. First, it is quite rare for endocarditis to present with headache as the primary complaint, a symptom that may have been related to the dissemination of septic emboli into meningeal vessels.…”

Section: Discussionmentioning

confidence: 75%

“…These results are similar to the case described by Barreto et al, in which the TTE was normal and the TEE showed significant valvular perforation with vegetation. 10 This illustrates the value of obtaining a TEE to assess for complications that may not be apparent on TTE. 11 Furthermore, the severity of thrombocytopenia was another interesting aspect of the patient's clinical presentation.…”

Section: Discussionmentioning

confidence: 94%

Section: Discussionmentioning

confidence: 99%

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Haemophilus parainfluenzae Endocarditis Associated With Maxillary Sinusitis and Complicated by Cerebral Emboli in a Young Man

Duzenli

Dwyer

Carey

2017

Journal of Investigative Medicine High Impact Case Reports

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HACEK endocarditis is often difficult to diagnose given the slow-growing characteristics of the organisms involved. Haemophilus parainfluenzae, one of the HACEK organisms, is an uncommon cause of endocarditis. We describe a case of a previously healthy young man with H parainfluenzae endocarditis that was associated with maxillary sinusitis and severe systemic complications, including septic cerebral emboli and mitral valve perforation. Previously reported cases have also described a predilection for younger people, cardiac valve pathology, and a high prevalence of stroke.

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Section: Discussionmentioning

confidence: 75%

Section: Discussionmentioning

confidence: 94%

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Haemophilus parainfluenzae Endocarditis Associated With Maxillary Sinusitis and Complicated by Cerebral Emboli in a Young Man

Duzenli

Dwyer

Carey

2017

Journal of Investigative Medicine High Impact Case Reports

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An aggressive form ofHaemophilus parainfluenzaeinfective endocarditis presenting with limb weakness

2018

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We present the case of a 49-year-old man with a bicuspid aortic valve who presented to the emergency department with limb weakness and a fever. Blood tests revealed a fulminant septic process with bacteraemia, anaemia and thrombocytopenia. Imaging revealed a cervical spinal abscess and discitis causing spinal cord compression, in addition to multiple cerebral septic emboli, pleural effusions and ascites. A transoesophageal echocardiogram (TOE) performed post decompression of his spinal collection showed native aortic valve endocarditis with an associated large aortic root abscess. He underwent successful aortic valve surgery and a 6-week course of antibiotic therapy and made an excellent clinical recovery with no long-term complications from his condition.

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Infective endocarditis caused by gram-negative bacteria

Чипигина¹,

Karpova²,

Kashentseva³

et al. 2022

Klinicist

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Infective endocarditis (IE) caused by Gram-negative bacteria is a rare and insufficiently characterized form of endocarditis. The literature review presents data on the frequency, course, risk factors, diagnosis and treatment of both IE caused by the HACEK microorganisms (Haemophilus spр., Aggregatibacter spp., Cardiobacterium hominis, Eikenella corrodens, Kingella) and other Gram-negative bacteria. Gram-negative bacteria are the cause of 3.6–13.6 % IE cases (HACEK microorganisms in 0.8–3 % of IE cases in adults, non-HACEK in 1.8–3.9 %). Patients with IE caused by the HACEK microorganisms are younger, their disease is not associated with previous in-hospital treatment and is subacute with favorable prognosis (intrahospital mortality is 2–3 %). HACEK microorganisms mostly retain sensitivity to many antibiotics. Risk factors of IE caused by HACEK microorganisms are dental interventions, heart disorders, valve prostheses and other implanted cardiac devices. IE caused by non-HACEK Gram-negative bacteria is more common in elderly with concomitant disorders and usually is acute; intrahospital mortality is 13–36.5 %. Risk factors of IE caused by non-HACEK microorganisms are valve prostheses, electrical pacemakers, venous and central catheters, recent in-hospital treatment, Gram-negative bacteremia, decreased immunity, drug abuse, urinary infection, alcoholism, cirrhosis of the liver, removed spleen, consequences of dog and cat bites, working with the soil. Among Gram-negative non-HACEK bacteria causing IE, 28 % have multi-drug resistance (MDR / XDR) against antibiotics. Therefore, Gram-negative bacteria rarely cause IE but during selection of empiric therapy in patients with IE with corresponding risk factors, probability of Gram-negative causative microorganisms in IE etiology should be taken into account.

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Haemophilus parainfluenzaeendocarditis with systemic embolisation following maxillary sinusitis

Cited by 4 publications

References 11 publications

Haemophilus parainfluenzae Endocarditis Associated With Maxillary Sinusitis and Complicated by Cerebral Emboli in a Young Man

Haemophilus parainfluenzae Endocarditis Associated With Maxillary Sinusitis and Complicated by Cerebral Emboli in a Young Man

An aggressive form ofHaemophilus parainfluenzaeinfective endocarditis presenting with limb weakness

Infective endocarditis caused by gram-negative bacteria

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