<i>Ex-Vivo</i>Ureteroscopy at the Time of Live Donor Nephrectomy

Schade, George R.; Wolf, J. Stuart; Faerber, Gary J.

doi:10.1089/end.2010.0627

Cited by 37 publications

(22 citation statements)

References 18 publications

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“…There are few case series which have shown that the short-and medium-term results are excellent both in donor and recipient follow-up after bench ureteroscopy [12][13][14][15][16][17][18]. We need long-term results with large number of patients to establish bench URS/RIRS as treatment of choice for this specific category of patients.…”

Section: Resultsmentioning

confidence: 99%

Endourological management of live donors with urolithiasis at the time of donor nephrectomy: a single center experience

Pushkar¹,

Agarwal²,

Kumar³

et al. 2015

Int Urol Nephrol

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Section: Resultsmentioning

confidence: 99%

Endourological management of live donors with urolithiasis at the time of donor nephrectomy: a single center experience

Pushkar¹,

Agarwal²,

Kumar³

et al. 2015

Int Urol Nephrol

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“…It should be emphasized that there are no diagnostic and therapeutic standards with respect to detection and treatment of nephrolithiasis in donor kidneys [2,3]. In clinical practice, ultrasonography and CT of the abdomen can detect nephrolithiasis if present prior to transplantation.…”

Section: Discussionmentioning

confidence: 99%

Ex Vivo Removal of Stones in Donor Kidneys by Flexible Ureteroscopy Prior to Renal Transplantation: A Case Report

et al. 2017

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Patient: Male, 33Final Diagnosis: Donation after cardiac death (DCD)Symptoms: NoneMedication:—Clinical Procedure: Ex vivo removal of stones in donor kidneys by flexible ureteroscopSpecialty: TransplantologyObjective:Rare co-existance of disease or pathologyBackground:Because of the shortage of grafts, many attempts have been made to treat calculi in donor kidneys and have achieved successful management. This case report is the first to present removal of stones from bilateral kidneys from a single donor through flexible ureteroscopy before transplantation.Case Report:The present case report shows the clinical management of bilateral donor kidneys with calculi, which were taken from a 33-year-old man through donation after cardiac death (DCD). Computed tomography showed 2 stones in the right donor kidney and 1 in the left donor kidney. Two stones were removed ex vivo using a flexible ureteroscope before transplantation, and the third one turned out to be a renal papillae calcification, which was left in place without surgical treatment. The bilateral donor kidneys were transplanted to 2 recipients.Conclusions:There is a possibility of increasing the kidney pool by using donor kidneys containing calculi, which should be removed before transplantation.

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“…Our results corroborate the findings of several studies that have demonstrated the safety and ease of performing ex-vivo ureteroscopy prior to renal implantation. 10,13,14 With regards to small renal masses, one patient with an incidentally discovered 2 cm AML underwent ex-vivo partial nephrectomy and renorrhaphy. Ex-vivo partial nephrectomy for incidentally discovered renal masses with subsequent renal implantation has been described previously, with several reports demonstrating its applicability to small renal cell carcinomas.…”

Section: Discussionmentioning

confidence: 99%

Expanding living kidney donor criteria with ex-vivo surgery for renal anomalies

McGregor

Rampersad

Patel

2016

CUAJ

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Introduction: Renal transplantation remains the gold standard treatment for end-stage renal disease, with living donor kidneys providing the best outcomes in terms of allograft survival. As the number of patients on the waitlist continues to grow, solutions to expand the donor pool are ongoing. A paradigm shift in the eligibility of donors with renal anomalies has been looked at as a potential source to expand the living donor pool. We sought to determine how many patients presented with anatomic renal anomalies at our transplant centre and describe the ex-vivo surgical techniques used to render these kidneys suitable for transplantation. Methods: A retrospective review was performed of all patients referred for surgical suitability to undergo laparoscopic donor nephrectomy between January 2011 and January 2015. Patient charts were analyzed for demographic information, perioperative variables, urological histories, and postoperative outcomes. Results: 96 referrals were identified, of which 81 patients underwent laparoscopic donor nephrectomy. Of these patients, 11 (13.6%) were identified as having a renal anomaly that could potentially exclude them from the donation process. These anomalies included five patients with unilateral nephrolithiasis, four patients with large renal cysts (>4 cm diameter), one patient with an angiomyolipoma (AML) and one patient with a calyceal diverticulum filled with stones. A description of the ex-vivo surgical techniques used to correct these renal anomalies is provided. Conclusions:We have shown here that ex-vivo surgical techniques can safely and effectively help correct some of these renal anomalies to render these kidneys transplantable, helping to expand the living donor pool.

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Ex-VivoUreteroscopy at the Time of Live Donor Nephrectomy

Abstract: ExURS safely renders live donor kidney allografts stone free with low risk of recurrence. When used appropriately, ExURS could safely increase the number of potential kidney donors and minimize the risk of adverse stone events.

Cited by 37 publications

References 18 publications

Endourological management of live donors with urolithiasis at the time of donor nephrectomy: a single center experience

Endourological management of live donors with urolithiasis at the time of donor nephrectomy: a single center experience

Ex Vivo Removal of Stones in Donor Kidneys by Flexible Ureteroscopy Prior to Renal Transplantation: A Case Report

Expanding living kidney donor criteria with ex-vivo surgery for renal anomalies

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